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Table 3 NNT, number whose depressive symptoms could benefit from exercise, and percentile improvement

From: Effects of exercise on depressive symptoms in adults with arthritis and other rheumatic disease: a systematic review of meta-analyses

Reference NNT (95% CI) Number Benefitting (95% CI) (millions)a U3Index (95% CI)b(Percentile Improvement)
Busch et al. (2006)[30] 6 (4, 13) 0.83 (1.25, 0.38) 22.9 (9.1, 33.9)
Hauser et al. (2010)[37] 9 (6, 23) 0.56 (0.83, 0.22) 12.6 (4.8, 20.2)
  1. Notes: NNT, number needed to-treat; 95% CI, 95% confidence intervals; a, gross estimate of the number of US people with fibromyalgia who could improve their depressive symptoms if they started and maintained a regular exercise program. Based on an estimated 5 million US people with fibromyalgia[4] and assuming that none exercise regularly; b, Cohen’s U3 Index[38].