Figure 7

H . E staining (magnification , x100) . At 2 weeks, the skull holes were filled with fibrous tissues in the control group (a), while cartilage islands and new bone formation was observed in the experimental group (A). At 4 weeks post-operatively, the trabecular bone in the control group (b) was small, sparse and mixed with cartilage islands and new bone formation, while in the experimental group (B), trabecular bone was relatively thick and dense. At 6 weeks post-operatively, the trabecular bone in the control group (c) became thick and dense, while, the trabecular bone in the experimental group (C) became lamellar bone. At 8 weeks postoperatively, lamellar bone was found in both groups (D and d).