Table 3 Osteogenic genes at least 3-fold upregulated or downregulated in osteoporotic bone tissue
From: Differences in osteogenic and apoptotic genes between osteoporotic and osteoarthritic patients
Gen symbol | ID gen(GeneBannk) | Function | Fold change |
|---|---|---|---|
BGLAP | NM_199173 | Skeletal Development | - 3.39 |
BMP5 | NM_ 001718 | Skeletal Development | - 3.87 |
BMP6 | NM_021073 | Skeletal Development | - 3.30 |
CDH11 | NM_001797 | Bone Mineral Metabolism | - 3.30 |
COL14A1 | NM_021110 | Bone Mineral Metabolism | - 9.54 |
COMP | NM_000095 | Bone Mineral Metabolism | - 4.63 |
EGFR | NM_005228 | Cell growth and differentiation | −5.28 |
FGF1 | NM_000800 | Cell growth and differentiation | 3.3 |
FGFR1 | NM_015850 | Cell growth and differentiation | - 5.95 |
FGFR2 | NM_000141 | Cell growth and differentiation | - 5.63 |
IGF1R | NM_000875 | Cell growth and differentiation | - 8.96 |
VEGFA | NM_003376 | Cell growth and differentiation | 3.00 |
TGFBR1 | NM_004612 | Cell Proliferation | - 6.31 |
TGFRB2 | NM_003242 | Cell Proliferation | - 7.04 |
VCAM1 | NM_001078 | Cell adhesion Molecules | - 8.36 |
MMP2 | NM_004530 | Extracellular matrix Proteases | - 4.36 |
MMP8 | NM_002424 | Extracellular matrix Proteases | 5.06 |
NFKB1 | NM_003998 | Transcription Factors and regulators | - 3.06 |
SMAD2 | NM_005901 | Transcription Factors and regulators | - 3.42 |
SMAD3 | NM_005902 | Transcription Factors and regulators | - 5.25 |
SOX9 | NM_000346 | Transcription Factors and regulators | - 5.00 |
RUNX-2 | NM_004348 | Transcription Factors and regulators | - 2.94 |
TNF | NM_000594 | Transcription Factors and regulators | - 9.18 |