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Table 5 Teriparatide utilization and overall utilization and costs in the 12 month follow-up period

From: Association of teriparatide adherence and persistence with clinical and economic outcomes in Medicare Part D recipients: a retrospective cohort study

Measure PDC* < 50% PDC 50% ≤ 80% PDC ≥ 80% Persistent Non-persistent
  (low adherent) (moderately adherent) (highly adherent)   (60 day gap)
Total Patients 541 57 163 181 580
Inpatient Hospitalizations      
  Members with Hospitalization n,(%) 116 (21.4%) 16 (28.1%) 26 (16.%) 31 (17.13%) 127 (21.9%)
  Hospitalizations Per Member** 0.4 (± 0.9) 0.5 (± 1.10) 0.2 (± 0.6) 0.3 (± 0.7) 0.4 (± 0.9)
  0 [0 - 6] 0 [0 - 5] 0 [0 - 4] 0 [0 - 4] 0 [0 - 6]
Emergency Room Visits      
  Members with Visit n,(%) Δ ¥ 180 (33.27%) 17 (29.82%) 39 (23.93%) 43 (23.76%) 193 (33.28%)
  Visits Per Member** 0.7 (± 1.8) 0.5 (± 0.8) 0.4 (± 1.1) 0.4 (± 1.04) 0.7 (± 1.7)
0 [0 - 30] 0 [0 - 3] 0 [0 - 9] 0 [0 - 9] 0 [0 - 30]
Outpatient Visits      
  Members with Visit n,(%) 540 (99.8%) 57 (100.0%) 163 (100.0%) 181 (100.0%) 579 (99.8%)
  Visits Per Member** 35.4 (± 34.2) 39. (± 39.8) 32.3 (± 28.6) 32.7 (± 29.7) 35.7 (± 34.6)
26 [0 - 320] 24 [1 - 192] 23 [3 - 195] 23 [3 - 195] 26 [0 - 320]
Pharmacy Claims      
  Members with Pharmacy Claim n,(%) 541 (100.0%) 57 (100.0%) 163 (100.0%) 181 (100.0%) 580 (100.0%)
  Pharmacy Claims Per Member** † ‡ 44.36 (± 31.01) 43.96 (± 28.70) 52.12 (± 35.06) 51.20 (± 34.72) 44.37 (± 30.79)
38 [1 - 214] 37 [4 - 127] 41 [6 - 186] 40 [6 - 186] 39 [1 - 214]
Total Healthcare Cost** † ‡ $15,528 (± $37,713) $25,574 (± $28,620) $21,033 (± $13,136) $21,046 (± $13,560) $16,341 (± $37,485)
$7,272 [$1,097 - $758,916] $15,124 [$6,403 - $172,809] $15,777 [$9,745 - $87,302] $15,777 [$7,901 - $87,302] $7,562 [$1,097 - $758,916]
  Inpatient Hospitalization Cost** $4,897 (± $26,941) $8,448 (± $21,125) $2,198 (± $7,342) $2,535 (± $7,961) $5,224 (± $26,775)
$0 [$0 - $562,430] $0 [$0 - $123,486] $0 [$0 - $57,410] $0 [$0 - $57,410] $0 [$0 - $562,430]
  Emergency Room Visit Cost** $465 (± $2,840) $330 (± $971) $211 (± $711) $205 (± $686) $461 (± $2,759)
$0 [$0 - $62,129] $0 [$0 - $5,486] $0 [$0 - $6,124] $0 [$0 - $6,124] $0 [$0 - $62,129]
  Outpatient Cost** $5,806 (± $8,860) $6,439 (± $8,880) $5,151 (± $6,428) $5,118 (± $6,290) $5,899 (± $8,950)
$2,689 [$0 - $91,816] $2,724 [$93 - $44,149] $2,740 [$0 - $34,442] $2,583 [$0 - $34,442] $2,771 [$0 - $91,816]
  Pharmacy Cost** † ‡ $4,361 (± $5,344) $10,358 (± $5,657) $13,472 (± $3,787) $13,187 (± $3,935) $4,757 (± $5,597)
$3,445 [$829 - $72,703] $8,915 [$5,902 - $40,300] $12,301 [$9,130 - $34,737] $12,080 [$5,839 - $34,737] $3,567 [$829 - $72,703]
  1. * Proportion of days covered.
  2. **Mean, standard deviation, median, [range].
  3. † ANOVA pairwise comparison between PDC < 50% and PDC ≥ 80% groups, p < 0.05.
  4. t-test between ‘Persistent’ and ‘Non-Persistent’ (60 Day Gap) groups, p < 0.05.
  5. Δ Chi-square comparison between PDC < 50% and PDC ≥ 80% groups, p < 0.05.
  6. ¥ Chi-square comparison between ‘Persistent’ and ‘Non-Persistent’ (60 Day Gap) groups, p < 0.05.