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Table 5 Teriparatide utilization and overall utilization and costs in the 12 month follow-up period

From: Association of teriparatide adherence and persistence with clinical and economic outcomes in Medicare Part D recipients: a retrospective cohort study

Measure

PDC* < 50%

PDC 50% ≤ 80%

PDC ≥ 80%

Persistent

Non-persistent

 

(low adherent)

(moderately adherent)

(highly adherent)

 

(60 day gap)

Total Patients

541

57

163

181

580

Inpatient Hospitalizations

     

  Members with Hospitalization n,(%)

116 (21.4%)

16 (28.1%)

26 (16.%)

31 (17.13%)

127 (21.9%)

  Hospitalizations Per Member**

0.4 (± 0.9)

0.5 (± 1.10)

0.2 (± 0.6)

0.3 (± 0.7)

0.4 (± 0.9)

 

0 [0 - 6]

0 [0 - 5]

0 [0 - 4]

0 [0 - 4]

0 [0 - 6]

Emergency Room Visits

     

  Members with Visit n,(%) Δ ¥

180 (33.27%)

17 (29.82%)

39 (23.93%)

43 (23.76%)

193 (33.28%)

  Visits Per Member**

0.7 (± 1.8)

0.5 (± 0.8)

0.4 (± 1.1)

0.4 (± 1.04)

0.7 (± 1.7)

0 [0 - 30]

0 [0 - 3]

0 [0 - 9]

0 [0 - 9]

0 [0 - 30]

Outpatient Visits

     

  Members with Visit n,(%)

540 (99.8%)

57 (100.0%)

163 (100.0%)

181 (100.0%)

579 (99.8%)

  Visits Per Member**

35.4 (± 34.2)

39. (± 39.8)

32.3 (± 28.6)

32.7 (± 29.7)

35.7 (± 34.6)

26 [0 - 320]

24 [1 - 192]

23 [3 - 195]

23 [3 - 195]

26 [0 - 320]

Pharmacy Claims

     

  Members with Pharmacy Claim n,(%)

541 (100.0%)

57 (100.0%)

163 (100.0%)

181 (100.0%)

580 (100.0%)

  Pharmacy Claims Per Member** † ‡

44.36 (± 31.01)

43.96 (± 28.70)

52.12 (± 35.06)

51.20 (± 34.72)

44.37 (± 30.79)

38 [1 - 214]

37 [4 - 127]

41 [6 - 186]

40 [6 - 186]

39 [1 - 214]

Total Healthcare Cost** † ‡

$15,528 (± $37,713)

$25,574 (± $28,620)

$21,033 (± $13,136)

$21,046 (± $13,560)

$16,341 (± $37,485)

$7,272 [$1,097 - $758,916]

$15,124 [$6,403 - $172,809]

$15,777 [$9,745 - $87,302]

$15,777 [$7,901 - $87,302]

$7,562 [$1,097 - $758,916]

  Inpatient Hospitalization Cost**

$4,897 (± $26,941)

$8,448 (± $21,125)

$2,198 (± $7,342)

$2,535 (± $7,961)

$5,224 (± $26,775)

$0 [$0 - $562,430]

$0 [$0 - $123,486]

$0 [$0 - $57,410]

$0 [$0 - $57,410]

$0 [$0 - $562,430]

  Emergency Room Visit Cost**

$465 (± $2,840)

$330 (± $971)

$211 (± $711)

$205 (± $686)

$461 (± $2,759)

$0 [$0 - $62,129]

$0 [$0 - $5,486]

$0 [$0 - $6,124]

$0 [$0 - $6,124]

$0 [$0 - $62,129]

  Outpatient Cost**

$5,806 (± $8,860)

$6,439 (± $8,880)

$5,151 (± $6,428)

$5,118 (± $6,290)

$5,899 (± $8,950)

$2,689 [$0 - $91,816]

$2,724 [$93 - $44,149]

$2,740 [$0 - $34,442]

$2,583 [$0 - $34,442]

$2,771 [$0 - $91,816]

  Pharmacy Cost** † ‡

$4,361 (± $5,344)

$10,358 (± $5,657)

$13,472 (± $3,787)

$13,187 (± $3,935)

$4,757 (± $5,597)

$3,445 [$829 - $72,703]

$8,915 [$5,902 - $40,300]

$12,301 [$9,130 - $34,737]

$12,080 [$5,839 - $34,737]

$3,567 [$829 - $72,703]

  1. * Proportion of days covered.
  2. **Mean, standard deviation, median, [range].
  3. † ANOVA pairwise comparison between PDC < 50% and PDC ≥ 80% groups, p < 0.05.
  4. ‡ t-test between ‘Persistent’ and ‘Non-Persistent’ (60 Day Gap) groups, p < 0.05.
  5. Δ Chi-square comparison between PDC < 50% and PDC ≥ 80% groups, p < 0.05.
  6. ¥ Chi-square comparison between ‘Persistent’ and ‘Non-Persistent’ (60 Day Gap) groups, p < 0.05.
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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