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Table 1 The patients’ preoperative characteristics data

From: Efficacy of low-dose intra-articular tranexamic acid in total knee replacement; a prospective triple-blinded randomized controlled trial

  Control group TXA-250 group TXA-500 group p-value
  (n = 45) (n = 45) (n = 45)  
Demographic characteristics    
  Age✝ (year) 66.2 (7.3) 67.6 (8.7) 68.1 (6.2) 0.44
  Female gender 43 (95.6%) 42 (93.3%) 40 (88.9%) 0.47
  Body mass index✝ (kg/m2) 26.3 (3.7) 26.2 (3.7) 27.3 (4.7) 0.37
  Estimated blood volume✝ (ml) 3146 (310) 3090 (246) 3227 (401) 0.14
  DM 34 (75.6%) 36 (80.0%) 34 (75.6%) 0.9
  ASA classification (II/III) (no. of patients) 29/16 20/25 20/25 0.1
Preoperative laboratory values
  Preoperative hemoglobin✝ (g/dL) 12.1 (1.1) 11.9 (1.0) 12.6 (1.3)*c 0.02*
Surgical characteristics
  Regional anesthesia 42 (93%) 39 (87%) 43 (96%) 0.38
  Right side 26 (57.8) 25 (55.6) 23 (51.1) 0.86
  Preoperative mechanical axis 4.9 varus (15 varus to 8 valgus) 5.0 varus (16 varus to 13 valgus) 5.2 varus (20 varus to 6 valgus) 0.97
  Operative time✝ (minute) 79.1 (14.3) 78.8 (13.0) 81.1 (13.1) 0.65
  Surgical incision✝ (cm) 12.5 (2.2) 12.3 (2.2) 13.2 (1.2 ) 0.09
Functional characteristics
  Preoperative KSK Score✝ 77.3 (11.0) 76.8 (11.9) 76.4 (13.3) 0.94
  Preoperative WOMAC score✝ 59.8 (9.5) 60.3 (9.8) 60.0 (9.7) 0.98
  1. ✝ = The values were presented as mean (standard deviation),  = The values were presented as mean (range).
  2.  = The values were presented as number of patients having that condition (percentage of this group).
  3. TXA; tranexamic acid, DM; patient having underlying diabetes mellitus, ASA; American Society of Anesthesiologists.
  4. KSK; Knee Society Knee, WOMAC; Western Ontario and McMaster Universities Osteoarthritis Index.
  5. * = p <0.05; c = comparison between TXA-250 and TXA-500 group with p < 0.05.