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Table 1 The patientsā€™ preoperative characteristics data

From: Efficacy of low-dose intra-articular tranexamic acid in total knee replacement; a prospective triple-blinded randomized controlled trial

 

Control group

TXA-250 group

TXA-500 group

p-value

 

(nā€‰=ā€‰45)

(nā€‰=ā€‰45)

(nā€‰=ā€‰45)

 

Demographic characteristics

   

ā€ƒ Ageāœ (year)

66.2 (7.3)

67.6 (8.7)

68.1 (6.2)

0.44

ā€ƒ Female genderā—†

43 (95.6%)

42 (93.3%)

40 (88.9%)

0.47

ā€ƒ Body mass indexāœ (kg/m2)

26.3 (3.7)

26.2 (3.7)

27.3 (4.7)

0.37

ā€ƒ Estimated blood volumeāœ (ml)

3146 (310)

3090 (246)

3227 (401)

0.14

ā€ƒ DMā—†

34 (75.6%)

36 (80.0%)

34 (75.6%)

0.9

ā€ƒ ASA classification (II/III) (no. of patients)

29/16

20/25

20/25

0.1

Preoperative laboratory values

ā€ƒ Preoperative hemoglobināœ (g/dL)

12.1 (1.1)

11.9 (1.0)

12.6 (1.3)*c

0.02*

Surgical characteristics

ā€ƒ Regional anesthesiaā—†

42 (93%)

39 (87%)

43 (96%)

0.38

ā€ƒ Right sideā—†

26 (57.8)

25 (55.6)

23 (51.1)

0.86

ā€ƒ Preoperative mechanical axisā—¼

4.9 varus (15 varus to 8 valgus)

5.0 varus (16 varus to 13 valgus)

5.2 varus (20 varus to 6 valgus)

0.97

ā€ƒ Operative timeāœ (minute)

79.1 (14.3)

78.8 (13.0)

81.1 (13.1)

0.65

ā€ƒ Surgical incisionāœ (cm)

12.5 (2.2)

12.3 (2.2)

13.2 (1.2 )

0.09

Functional characteristics

ā€ƒ Preoperative KSK Scoreāœ

77.3 (11.0)

76.8 (11.9)

76.4 (13.3)

0.94

ā€ƒ Preoperative WOMAC scoreāœ

59.8 (9.5)

60.3 (9.8)

60.0 (9.7)

0.98

  1. āœā€‰=ā€‰The values were presented as mean (standard deviation), ā—¼ā€‰=ā€‰The values were presented as mean (range).
  2. ā—†ā€‰=ā€‰The values were presented as number of patients having that condition (percentage of this group).
  3. TXA; tranexamic acid, DM; patient having underlying diabetes mellitus, ASA; American Society of Anesthesiologists.
  4. KSK; Knee Society Knee, WOMAC; Western Ontario and McMaster Universities Osteoarthritis Index.
  5. *ā€‰=ā€‰p <0.05; cā€‰=ā€‰comparison between TXA-250 and TXA-500 group with pā€‰<ā€‰0.05.