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Table 4 Patient characteristics of MC + and MC- SLE patients at study entry

From: Long-term persistence and effects of fetal microchimerisms on disease onset and status in a cohort of women with rheumatoid arthritis and systemic lupus erythematosus

 

MC + SLE

MC- SLE

all SLE

Mean age (SEM)

51.2* (3.4)

57.1* (3.7)

55.2 (2.7)

  min-max

42-58

45-82

42-82

  95% CI of SEM

41.6/60.8

48.9/65.5

49.8/60.7

Mean age at disease onset (SEM)

42.6 *(3.8)

49.1* (4.5)

46.9 (3.3)

  min-max

35-54

27-75

27-75

  95% CI of SEM

32.1/53.1

39.0/59.2

40.0/54.0

Mean age at birth of first son (SEM)

24.0* (2.4)

26.4* (1.6)

24.7 (1.3)

  min-max

18-31

22-38

18-38

  95% CI of SEM

16.3/31.7

22.7/30.1

22.8/28.7

ANA titer (Median)

1:640

1:640

1:640

  (n = 10 MC- n = 4 MC+)

   

  min-max

160-2560

160-2560

160-2560

dsDNA-antibodies present

0 / 3 (0%)

3 / 10 (30%)

3 / 13 (23%)

C3 (g/l) Mean (n = 9 MC-, n = 2 MC+)

1.47

1.28

1.32

min-max

1.45-1.50

0.94-1.55

0.94-1.55

C4 (g/l) Mean (n = 9 MC-, n = 2 MC+)

0.28

0.23

0.24

min-max

0.22-0.35

0.13-0.33

0.13-0.35

CH50 Mean (U/ml)

56.8

51.4

52.3

(n = 9 MC-, n = 2 MC+) min-max

52.7-60.9

42.1-59.1

42.1-60.9

  1. Normal ranges: C3 0.9-1.8 g/l; C4 0.1-0.4 g/l; CH50 23–46 U/ml; ANA: 1:80–1:320 (+ - ++), 1:640–1:1280 (+++), >1:2560 (++++); dsDNA Ab: < 100 RE/ml; *p (MC + vs. MC-) not statistically significant.