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Table 1 Main characteristics of the 22 studies included in the final meta-analysis

From: Meta-analysis of the association of HLA-DRB1 with rheumatoid arthritis in Chinese populations

Author(reference)

Year

Region

Source of cases

Source of controls

Detection methods

Number of cases

Number of controls

Quality score

Ye SX [13]

1989

Liaoning

Hospital-based

Population-based

NS

39

100

22

Molkentin, J [14]

1993

Shanghai

Hospital-based

Population-based

PCR-SSP

23

21

26

Zhu NS [15]

1994

Shanghai

Hospital-based

Population-based

PCR-RFLP

95

130

24

Wang BL [16]

1996

Anhui

Hospital-based

Population-based

PCR-SSP

30

30

17

Xiao Z [17]

1997

Inner Mongolia

Hospital-based

Population-based

NS

41

50

16

Zhao Y [18]

1997

Beijing

Hospital-based

Population-based

PCR-SSP

86

106

21

Gu JR [19]

1998

Guangdong

Hospital-based

Population-based

PCR-SSP

47

108

23

Yuan GH [8]

1998

Beijing

Hospital-based

Population-based

PCR-RFLP

35

100

23

Zhang JQ [20]

1999

Hebei

Hospital-based

Population-based

PCR-SSP

180

100

25

Liu QH [6]

2000

Hubei

Hospital-based

Population-based

PCR-SSP

78

126

26

Wu H [21]

2001

Hunan

Hospital-based

Population-based

PCR-SSP

105

76

32

Lin L[22]

2001

Guangdong

Hospital-based

Population-based

PCR-SSP

117

100

21

Liu YJ [23]

2002

Guizhou

Hospital-based

Population-based

PCR-SSP

35

51

22

Li XF [9]

2003

Shandong

Hospital-based

Population-based

PCR-SSP

132

130

31

Zhang SL[24]

2003

Fujian

Hospital-based

Population-based

PCR-SSP

98

100

21

Su Y [25]

2004

Beijing

Hospital-based

Hospital-based

PCR-SSP

136

79

24

Duan JM [26]

2005

Anhui

Hospital-based

Population-based

PCR-SSP

25

77

23

Zhang HW [7]

2005

Guangdong

Hospital-based

Population-based

PCR-SSP

22

31

22

Chen CP [27]

2010

Shanxi

Hospital-based

Population-based

PCR-SSP

42

14

21

Wang CF [28]

2010

Gansu

Hospital-based

Population-based

PCR-SSP

27

46

21

Chang ZF [29]

2012

Inner Mongolia

Hospital-based

Population-based

PCR-SSP

140

100

23

Shi YM [30]

2012

Xinjiang

Hospital-based

Population-based

PCR-SSP

157

118

21

  1. 'PCR-SSP’ stands for Polymerase Chain Reaction-Sequence-Specific Primers, 'PCR-RFLP’ stands for Polymerase Chain Reaction-Restriction Fragment Length Polymor Phism and 'NS’ corresponds to not stated.