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Table 1 Main characteristics of the 22 studies included in the final meta-analysis

From: Meta-analysis of the association of HLA-DRB1 with rheumatoid arthritis in Chinese populations

Author(reference) Year Region Source of cases Source of controls Detection methods Number of cases Number of controls Quality score
Ye SX [13] 1989 Liaoning Hospital-based Population-based NS 39 100 22
Molkentin, J [14] 1993 Shanghai Hospital-based Population-based PCR-SSP 23 21 26
Zhu NS [15] 1994 Shanghai Hospital-based Population-based PCR-RFLP 95 130 24
Wang BL [16] 1996 Anhui Hospital-based Population-based PCR-SSP 30 30 17
Xiao Z [17] 1997 Inner Mongolia Hospital-based Population-based NS 41 50 16
Zhao Y [18] 1997 Beijing Hospital-based Population-based PCR-SSP 86 106 21
Gu JR [19] 1998 Guangdong Hospital-based Population-based PCR-SSP 47 108 23
Yuan GH [8] 1998 Beijing Hospital-based Population-based PCR-RFLP 35 100 23
Zhang JQ [20] 1999 Hebei Hospital-based Population-based PCR-SSP 180 100 25
Liu QH [6] 2000 Hubei Hospital-based Population-based PCR-SSP 78 126 26
Wu H [21] 2001 Hunan Hospital-based Population-based PCR-SSP 105 76 32
Lin L[22] 2001 Guangdong Hospital-based Population-based PCR-SSP 117 100 21
Liu YJ [23] 2002 Guizhou Hospital-based Population-based PCR-SSP 35 51 22
Li XF [9] 2003 Shandong Hospital-based Population-based PCR-SSP 132 130 31
Zhang SL[24] 2003 Fujian Hospital-based Population-based PCR-SSP 98 100 21
Su Y [25] 2004 Beijing Hospital-based Hospital-based PCR-SSP 136 79 24
Duan JM [26] 2005 Anhui Hospital-based Population-based PCR-SSP 25 77 23
Zhang HW [7] 2005 Guangdong Hospital-based Population-based PCR-SSP 22 31 22
Chen CP [27] 2010 Shanxi Hospital-based Population-based PCR-SSP 42 14 21
Wang CF [28] 2010 Gansu Hospital-based Population-based PCR-SSP 27 46 21
Chang ZF [29] 2012 Inner Mongolia Hospital-based Population-based PCR-SSP 140 100 23
Shi YM [30] 2012 Xinjiang Hospital-based Population-based PCR-SSP 157 118 21
  1. 'PCR-SSP’ stands for Polymerase Chain Reaction-Sequence-Specific Primers, 'PCR-RFLP’ stands for Polymerase Chain Reaction-Restriction Fragment Length Polymor Phism and 'NS’ corresponds to not stated.