Figure 3

Histological parameters in wild type and mdx mice. (A) Percentage of muscle fibres with internalised nuclei determined in the diaphragm, M. soleus and M. tibialis anterior of wild type (black bars) and mdx mice (white bars) at 6 month of age. (B) Mean minimal Feret’s diameter determined in the diaphragm, M. soleus and M. tibialis anterior of wild type (black bars) and mdx mice (white bars) at 6 month of age. (C) Mean variance coefficient determined in the diaphragm, M. soleus and M. tibialis anterior of wild-type (black bars) and mdx mice (white bars) at 6 month of age. (D-F) Fibre size distribution determined as percentage of the total fibre number in the diaphragm (D), M. soleus (E) and M. tibialis anterior (F) of wild-type (black bars) and mdx mice (white bars) at 6 month of age. Data are shown as mean ± SD; n ≥ 7 mice; 1300–4300 myofibres per group; *p < 0.05, **p < 0.001 unpaired t-test.