Table 1 Baseline characteristics
Variables | Controls | HIV (+) Patients at baseline | p- value |
|---|---|---|---|
(n = 40) | (n = 40) | ||
Female/ Male | 5/35 | 5/35 | |
Age (mean years) | 37.19 ± 10.34 | 37.30 ± 9.92 | 0.756 |
BMI (mean kg/ m 2 ) | 23.43 ± 3.35 | 22.32 ± 3.85 | 0.225 |
Duration of HIV infection (mean years) | NA | 5.85 ± 3.07 | |
Viral load* (log10 copies/ mL) | NA | 4.42 (3.59-4.86) | |
CD4 + T cell count* (cells/ μl) | NA | 137 (63–204) | |
CD4 + T cell percentage (%) | NA | 10.78 ± 6.84 | |
CD8 + T cell counts* (cells/ μl) | NA | 773 (539–1027) | |
CD8 + T cell percentage (%) | NA | 57.73 ± 9.77 | |
BMD (mean g/ cm 2 ) | |||
Lumbar spine | 1.195 ± 0.139 | 1.138 ± 0.112 | 0.047 |
Femoral neck | 1.035 ± 0.166 | 0.972 ± 0.136 | 0.069 |
Total hip | 1.060 ± 0.126 | 1.015 ± 0.147 | 0.146 |
BMD (mean Z score) | |||
Lumbar spine | 0.654 ± 1.077 | 0.511 ± 0.838 | 0.498 |
Femoral neck | 0.382 + 1.189 | 0.255 ± 1.018 | 0.591 |
Total hip | 0.377 ± 1.157 | 0.244 ± 1.102 | 0.604 |
β-CTX (mean ng/ mL) | 0.42 ± 0.19 | 0.31 ± 0.16 | 0.008 |
P1NP (mean ng/ mL) | 55.82 ± 26.87 | 32.96 ± 14.00 | 0.000 |
PTH (mean pg/ mL) | 22.92 ± 10.17 | 41.78 ± 16.11 | 0.000 |
25- OH vitamin D (mean ng/ mL) | 19.12 ± 9.00 | 15.93 ± 6.49 | 0.073 |