Skip to main content

Table 5 Absolute risk difference for kOA from exposure to a higher BMI, manual occupation and combination at 53y

From: Body mass index, occupational activity, and leisure-time physical activity: an exploration of risk factors and modifiers for knee osteoarthritis in the 1946 British birth cohort

   Men Women
   Non-manual Manual Non-manual Manual
   % (95% CI) % (95% CI) % (95% CI) % (95% CI)
BMI (z-score) 0 Reference + 6.6 (2.0,14.6) Reference + 8.8 (6.1,12.7)
  +1 +3.0 (1.0,5.3) + 11.8 (4.1,22.7) +9.2 (6.8,16.8) + 21.7 (12.2,32.8)
  1. Absolute risk difference represented as % (95% CI); based on baseline risk of 7.5% and 12.8% in men and women respectively (see Table 1). Adjusted model based estimates (logistic); adjusted for potential confounders - education at 26y, income at 53y, childhood social class, family history of arthritis, history of knee injury and health status at 53y.