Figure 3From: Muscle wasting associated with pathologic change is a risk factor for the exacerbation of joint swelling in collagen-induced arthritis in cynomolgus monkeys Sequential changes of histopathologic feature of quadriceps femoris in HE staining. A: naive animal, B: necrosis and degeneration (↑) of muscle fiber and inflammatory cell infiltration at Week 2, C: degeneration and atrophy (↑) of muscle fiber at Week 3, which is clearer than that at Week2, D: regeneration (↑) of muscle fiber at Week 5, E: regeneration and atrophy (↑) at Week 9 similar to, but a lesser degree to that at Week 5 (E).Back to article page