Figure 2

Time course of static gait parameters in mice with (A, B, E and F) phosphate buffered saline (PBS) or (C, D, G and H) complete Freund’s adjuvant (CFA)-injected intra-articularly in the right hind (RH) limb i.e. paw pressure measured as light intensity (arbitrary units) (A and C) and ratio of light intensity between RH and left hind(LH) limbs (B and D), print area (E and G) and ratio of print area between RH and LH limbs (F and H). Each point represents the mean ± S.E.M of the values obtained from 7 (PBS) to 12 (CFA) animals. Statistically significant differences between RH and LH at the same time point post-CFA administration (C and G) * p < 0.05 and. ^** p < 0.01 (repeated measures two-way ANOVA followed by Bonferroni post-tests) and in comparison with ratio of RH/LH paw pressure or print area before CFA injection (D and H): ^* p < 0.05 and ^** p < 0.01(one-way ANOVA followed by Dunnett's Multiple Comparison Test).