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Table 5 Patients with “evident” and “considerable” local effects following 1 or 2 injections for Dupuytren’s contracture

From: Multiple concurrent collagenase clostridium histolyticum injections to dupuytren’s cords: an exploratory study

Number of Patients (%)

Local Treatment Effect

Maximum Severitya

PERIOD 1 (1 CCH injection) (n = 12)

PERIOD 2 (2 CCH injections) (n = 12)

  

Day 2

Day 7

Day 30

Day 2

Day 7

Day 30

Bruising

Evident

9 (75)

2 (17)

0

6 (50)

3 (25)

0

Considerable

 

1 (8)

0

0

3 (25)

1 (8)

0

Swelling

Evident

2 (17)

1 (8)

0

6 (50)

3 (25)

0

Considerable

 

5 (42)

0

0

2 (17)

0

0

Pain

Evident

5 (42)

0

0

3 (25)

0

0

Considerable

 

0

0

0

2 (17)

0

0

Lymphadenopathy

Evident

3 (25)

0

0

1 (8)

0

0

Considerable

 

0

0

0

1 (8)

0

0

Pruritus

Evident

3 (25)

0

0

0

0

0

Considerable

 

0

0

0

2 (17)

0

0

  1. CCH = collagenase clostridium histolyticum.