Macroscopic and immunostaining of regenerated cartilage after implantation. Postoperative appearance of repaired osteochondral defects in old rabbits implanted with scaffolds seeded with either nontransfected (top panels) or hTERT- and GRP78-transfected ORA chondrocytes (bottom panels) either 8 (A, D) or 16 (B, E) weeks after surgery. Immunostaining of type II collagen in tissue sections from rabbits implanted with scaffolds seeded with nontransfected (C) or hTERT- and GRP78-transfected (F) ORA chondrocytes. Each micrograph is representative of 8 tissue samples. Scale bar = 1.0 mm.