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Table 2 VDRs and VDRl mRNA concentration in female and male population of group B-AIS

From: Vitamin D Receptor gene (VDR) transcripts in bone, cartilage, muscles and blood and microarray analysis of vitamin D responsive genes expression in paravertebral muscles of Juvenile and Adolescent Idiopathic Scoliosis patients

  

Group B (15 females)

Group B (5 males)

U-Mann Whitney

Sample

Isoform

Average

Median

Range

St. dev

Average

Median

Range

St. dev

p

B1

VDRl

0

0

0

 

0

0

0

  

VDRs

240

150

11-746

300.5

7

7

2-13

7.3

0.09

B2

VDRl

0

0

0

 

0

0

0

  

VDRs

271

189

35-663

262

36

36

33-40

4.6

0.06

C1

VDRl

0

0

0

 

0

0

0

  

VDRs

1317

92

24-6193

2726.9

142

142

4-280

195.6

0.43

C2

VDRl

57

57

57

 

0

0

0

  

VDRs

3490

82

7-34119

10762

101

101

14-188

123.4

0.83

M1

VDRl

33

36

4-58

23.4

176

176

4-347

242.1

0.83

VDRs

268

50

6-1649

561

290

375

8-487

250.4

0.95

M2

VDRl

49

43

3-132

43.6

77

77

37-117

56.8

0.79

VDRs

641

17

1-4902

1612.5

372

165

44-906

466.8

0.50

Blood

VDRl

1215

1215

4-2427

1713.4

833

833

833

  

VDRs

695

695

30-1361

941.3

2621

2621

1800-3442

1160.6

0.04

  1. Comparison of QRT-RTPCR results obtained from homonymous tissue samples (B1-bone from concavity, B2-bone from convexity, C1-cartilage from concavity, C2-cartilage from convexity, M1-muscles from concavity, M2-muscles from convexity, blood) between females (n=15) and males (n=5) in group B – Adolescent Idiopathic Scoliosis , p<0,05 was considered as a statistically significant (nonparametric Mann Whitney U test).