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Figure 4 | BMC Musculoskeletal Disorders

Figure 4

From: Influence of Statins locally applied from orthopedic implants on osseous integration

Figure 4

a) Histomorphometric analysis. Total bone/implant contact was significantly decreased between the uncoated control and both experimental groups (SIM high: p < 0.001; SIM low: p = 0.006) as well as between PDLLA and SIM high (p < 0.001) (*). b) Direct bone/implant contact showed significant differences between SIM high and both control groups (vs. uncoated: p = 0.001; vs. PDLLA: p = 0.006) (*). c) Indirect bone/implant contact was reduced for both SIM coated groups, differing significantly between the PDLLA and SIM high group (p = 0.004) (*). d) Newly formed bone (within a 0.3mm range around the implants) was significantly reduced between uncoated controls and all other groups (vs. PDLLA: p = 0.002; vs. SIM low and –high: p < 0.001, respectively), as well as between PDLLA and SIM high implants (p = 0.002) (*).

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