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Table 1 Studies comparing level of aerobic capacity in RA patients and a healthy reference population

From: Are persons with rheumatoid arthritis deconditioned? A review of physical activity and aerobic capacity

Study (ref nr)

n (% F)

Reference Population n (% F)

Patient characteristics

VO2max RA patients versus reference population (ml/kg.min) p: significant difference

   

Setting

Age [range]

Body Composition

Disease duration

Impairment (FC I-IV)

 

de Carvalho 2003 MT [22]

35 (88.6%)

35♣ (?) hospital staff

Rheumatology clinic

47,85 (8,29)

?

8

FCI: 40% FCII: 51% FCIII: 8.6%

FC I: 24.89 (n=7) FC II: 21.86 (n=6)/24.28 (n=22)

NS

Ekdahl 1992 SMB [28]

67 (62.7%)

77♥ (61.0%) personnel

?

53.0 (10.2)

female: 164.1 (5.6) cm female: 66.1 (11.6) kg male: 177.9 (6.8) cm male: 75.6 (10.7 kg

10.6 (7.8)

FCII

female younger than 54 jr: 22.3±6.8 / 31.7±12.1 older than 54 jr: 18.7±3.5/21.9±5.3 male younger than 54 jr: 24.0±4.3/27.6±7.4 older than 54 jr: 18.7±4.1 / 25.1±6.1

p<0.001 p<0.001 p<0.001 p<0.001

Häkkinnen 2002 MB [23]

23 (100%) ERA LRA

12â™  (100%) area residence

Hospital

ERA: 41 (9) LRA: 49 (7)

ERA: 165 (9) cm 61 (13) kg fat: 30.4 (6.6) % LRA: 164 (7) cm 65 (13) kg fat: 34.3 (7.3) %

ERA: 2.9 (0.6) LRA: 14.5 (4.5)

FCI, II

ERA: 26.7±6.8/LRA: 23.1±6.1/controls: 24.8±2.3

NS

Kurtais 2006 MT [24]

19 (100%)

15♥ (100%) ?

Rehabilitation centre

48.3 (8.4)

?

128.8 (85.6) months

FCI, II

23.7±4.9 / 26.6±6.0

NS

Rall 1996 MB [25]

8 (62.5%)

exercise young : 8 (62.5%) old: 8 (62.5%) control old: 6 (66.7%) ♦

Rheumatology clinic

RA: 41.8±12.6 exercise young : 25.8±2.5 old : 70.3±5.0 control old 68.8±2.9

65.9 (15.9) kg BMI: 25.0 (4.3)

14.6 (12.5)

FC: 2.2 (0.8)

22.9±4.2 / young exercise group: 40.2±10.3 old exercise group: 20.7±5.0

old no exercise group: 21.7±5.7 young exercise versus other groups

p<0.001

  1. Age, body composition, disease duration are expressed as mean (standard deviation) if not expressed otherwise, VO2max is expressed as mean ± standard deviation. Age and disease duration are expressed in years. n: number of participants with RA or in reference population, MB: maximal bicycle test, MT: maximal treadmill test, SMB: sub-maximal bicycle test, %F: percentage females, FC: Functional Class, GP: general population, BMI: body mass index, RA: rheumatoid arthritis, ERA: early RA, LRA: late RA, ml/kg.min: milliliter per kilogram per minute. Controls matched on ♣: sex, age, body mass index, ♠: age, ♥: age, sex,♦: no information on matching.
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BMC Musculoskeletal Disorders

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