Table 2 Outcome measures

Pain subscale

WOMAC osteoarthritis score

Secondary Outcomes

- Stiffness and disability subscale

- WOMAC osteoarthritis score

- Knee pain

- Visual Analogue Scale (0–10 cm)

- Function and progression of OA

- Lequesne’s algofunctional questionnaire score

- Six-minute walk test result

- Distance (m)

- Paracetamol (500 mg) intake

- Days and amount of paracetamol ingested over six months

- Knee load during gait

- Knee adduction moment (%body weight/height) by inverse dynamics during gait

- Global medical assessment

- Ordinal scale (1-much worse, 2-slightly worse, 3-no change, 4-slightly better, 5-much better)

- Global patient’s self-assessment

- Ordinal scale (1-much worse, 2-slightly worse, 3-no change, 4-slightly better, 5-much better)