Figure 6

Cytokine levels in blood sera of LPS-treated and control LPS-untreated B10.BR males. Values of TNFα, IL-6, IFNγ, TGFβ and IL-10 represent the mean ± SD. IL-6 and IL-10 were significantly increased in LPS-treated males after the second and the fourth LPS dose, TNFα after the fourth LPS dose (A, B). No significant differences in cytokine levels were found at the end of the experiment, i.e. 20–22 weeks after the fourth LPS dose (C). TGFβ and in some cases IFNγ and IL-10 were under the limit of the detection kit. * p < 0.05, ** p < 0.01.