Table 7 Change in collagen gene expression in human tendinopathy
Gene Symbol | Description | Â | p-value | q-value | Fold Change |
|---|---|---|---|---|---|
Regulated | Â | Â | Â | Â | Â |
COL1A1 | Collagen, type I, alpha 1 | Expressed | 9.37E-03 | 3.96E-02 | 1.7 |
COL1A2 | Collagen, type I, alpha 2 | Expressed | 4.45E-03 | 3.16E-02 | 1.6 |
COL3A1 | Collagen, type III, alpha 1 | Expressed | 1.50E-02 | 4.28E-02 | 2.0 |
COL4A1 | Collagen, type IV, alpha 1 | Expressed | 1.91E-02 | 4.53E-02 | 2.7 |
COL4A2 | Collagen, type IV, alpha 2 | Expressed | 6.09E-03 | 3.16E-02 | 2.3 |
COL5A1 | Collagen, type V, alpha 1 | Expressed | 1.20E-02 | 4.28E-02 | 2.0 |
COL5A2 | Collagen, type V, alpha 2 | Expressed | 3.99E-03 | 3.16E-02 | 2.1 |
COL5A3 | Collagen, type V, alpha 3 | Expressed | 3.02E-03 | 3.16E-02 | 2.0 |
COL6A1 | Collagen, type VI, alpha 1 | Expressed | 2.93E-02 | 6.18E-02 | 1.8 |
COL6A2 | Collagen, type VI, alpha 2 | Expressed | 3.62E-02 | 6.89E-02 | 1.8 |
COL6A3 | Collagen, type VI, alpha 3 | Expressed | 5.45E-03 | 3.16E-02 | 1.7 |
COL8A1 | Collagen, type VIII, alpha 1 | Expressed | 2.49E-02 | 5.57E-02 | 2.0 |
COL8A2 | Collagen, type VIII, alpha 2 | Expressed | 1.48E-02 | 4.28E-02 | 1.8 |
COL10A1 | Collagen, type X, alpha 1 | Expressed | 1.69E-02 | 4.28E-02 | 2.1 |
COL12A1 | Collagen, type XII, alpha 1 | Expressed | 4.10E-03 | 3.16E-02 | 2.1 |
COL18A1 | Collagen, type XVIII, alpha 1 | Expressed | 6.65E-03 | 3.16E-02 | 2.2 |
COL27A1 | Collagen, type XXVII, alpha 1 | Expressed | 1.20E-03 | 3.16E-02 | 2.5 |
Not Regulated | Â | Â | Â | Â | Â |
COL7A1 | Collagen, type VII, alpha 1 | Expressed | 0.96 | 0.96 | 1.0 |
COL11A1 | Collagen, type XI, alpha 1 | Expressed | 0.58 | 0.71 | 1.2 |
COL15A1 | Collagen, type XV, alpha 1 | Expressed | 0.51 | 0.64 | 1.2 |
COL16A1 | Collagen, type XVI, alpha 1 | Expressed | 0.12 | 0.19 | 1.4 |
COL21A1 | Collagen, type XXI, alpha 1 | Expressed | 0.34 | 0.45 | 1.4 |
Expressed below limited of detection | Â | Â | Â | Â | Â |
COL2A1 | Collagen, type II, alpha 1 | - | 0.21 | 0.31 | 0.5 |
COL4A3 | Collagen, type IV, alpha 3 | - | 0.15 | 0.23 | 0.6 |
COL4A4 | Collagen, type IV, alpha 4 | - | 0.90 | 0.96 | 1.0 |
COL4A5 | Collagen, type IV, alpha 5 | - | 0.71 | 0.84 | 0.9 |
COL4A6 | Collagen, type IV, alpha 6 | - | 0.94 | 0.96 | 1.0 |
COL9A1 | Collagen, type IX, alpha 1 | - | 0.94 | 0.96 | 1.0 |
COL9A2 | Collagen, type IX, alpha 2 | - | 0.05 | 0.08 | 1.9 |
COL11A2 | Collagen, type XI, alpha 2 | - | 0.12 | 0.19 | 0.7 |
COL13A1 | Collagen, type XIII, alpha 1 | - | 0.08 | 0.13 | 2.0 |
COL14A1 | Collagen, type XIV, alpha 1 | - | 0.02 | 0.04 | 1.8 |
COL17A1 | Collagen, type XVII, alpha 1 | - | 0.33 | 0.45 | 1.3 |
COL19A1 | Collagen, type XIX, alpha 1 | - | 0.02 | 0.04 | 0.5 |
COL22A1 | Collagen, type XXII, alpha 1 | - | 0.03 | 0.07 | 0.5 |
COL23A1 | Collagen, type XXIII, alpha 1 | - | 0.75 | 0.84 | 1.0 |
COL24A1 | Collagen, type XXIV, alpha 1 | - | 0.33 | 0.45 | 1.3 |
COL25A1 | Collagen, type XXV, alpha 1 | - | 0.76 | 0.84 | 0.9 |