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Table 3 Top regulated transcripts in human tendinopathy as determined by microarray analysis

From: Regulation of gene expression in human tendinopathy

Gene Symbol Description p-value q-value Fold Change
ADAM12 A disintegrin and metalloproteinase domain 12 1.57E-05 2.09E-04 5.6
AP3M1 Adaptor-related protein complex 3, mu 1 subunit 1.24E-03 1.91E-03 1.7
ARL7 ADP-ribosylation factor-like 7 1.43E-03 2.11E-03 4.0
ARPC5 Actin related protein 2/3 complex, subunit 5 3.63E-05 2.10E-04 1.8
ASXL1 Additional sex combs like 1 (Drosophila) 1.11E-03 1.78E-03 1.8
ATP6V1A ATPase, H+ transporting, lysosomal 70 kDa 4.18E-05 2.10E-04 2.5
BACE2 Beta-site APP-cleaving enzyme 2 3.17E-06 8.01E-05 1.9
BNC2 Basonuclin 2 1.08E-04 3.15E-04 2.9
CA12 Carbonic anhydrase XII 3.57E-05 2.10E-04 2.8
CTHRC1 Collagen triple helix repeat containing 1 5.20E-04 1.10E-03 4.4
DDEF1 Development and differentiation enhancing factor 2.83E-05 2.10E-04 2.1
DOCK10 Dedicator of cytokinesis 10 7.91E-03 8.11E-03 3.3
EDIL3 EGF-like repeats and discoidin I-like domains 3 4.80E-03 5.34E-03 2.9
FOXP1 Forkhead box P1 4.67E-05 2.10E-04 1.7
GPR161 G protein-coupled receptor 161 2.76E-04 6.89E-04 1.9
IGFBP3 Insulin-like growth factor binding protein 3 7.29E-03 7.67E-03 3.5
IL13RA2 Interleukin 13 receptor, alpha 2 2.80E-03 3.50E-03 3.5
ILK Integrin-linked kinase 1.00E-04 3.15E-04 1.6
IQGAP1 IQ motif containing GTPase activating protein 1 4.73E-05 2.10E-04 1.5
ITGB1 Integrin, beta 1 3.52E-04 8.29E-04 1.7
ITPKB Inositol 1,4,5-trisphosphate 3-kinase B 7.37E-04 1.34E-03 2.5
JAG1 Jagged 1 (Alagille syndrome) 1.90E-03 2.52E-03 3.1
KCNE4 Potassium voltage-gated channel 4 8.19E-03 8.19E-03 3.4
LAMA4 Laminin, alpha 4 6.73E-04 1.31E-03 3.4
LRRC15 Leucine rich repeat containing 15 3.50E-03 4.24E-03 3.2
LRRC17 Leucine rich repeat containing 17 1.74E-03 2.40E-03 2.8
MARCKS Myristoylated alanine-rich kinase C substrate 3.93E-03 4.50E-03 2.8
NOTCH3 Notch homolog 3 (Drosophila) 1.65E-03 2.36E-03 3.6
PDIR protein disulfide isomerase-related 4.86E-04 1.08E-03 2.1
POSTN Periostin, osteoblast specific factor 1.10E-04 3.15E-04 3.5
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 1.01E-03 1.68E-03 2.1
S100A10 S100 calcium binding protein A10 1.95E-03 2.52E-03 2.8
SIN3A SIN3 homolog A, transcription regulator (yeast) 9.51E-05 3.15E-04 1.7
SLC2A13 Solute carrier family 2 13 5.41E-03 5.85E-03 2.8
TAOK1 TAO kinase 1 1.51E-04 4.03E-04 1.7
TJP1 Tight junction protein 1 (zona occludens 1) 6.87E-04 1.31E-03 1.6
TNC Tenascin C (hexabrachion) 9.20E-05 3.15E-04 5.3
UBE2E3 Ubiquitin-conjugating enzyme E2E 3 8.72E-04 1.52E-03 3.7
WDR1 WD repeat domain 1 4.01E-06 8.01E-05 1.6
WISP1 WNT1 inducible signaling pathway protein 1 3.93E-03 4.50E-03 3.4