Table 2 Synovial fluid biomarker concentrations (pg/μg of total protein) of osteoarthritic knees with and without effusion
From: Biochemical comparison of osteoarthritic knees with and without effusion
| Non-Effused (n = 11) | Effused (n = 11) | |||
|---|---|---|---|---|
| Biomarker | Median (95% CI) | Median (95% CI) | p value | r |
| IL-1β |
0.000009 (0.000003 - 0.000023) |
0.000012 (0.000006 - 0.000020) | 0.714 | -0.078 |
| IL-10 |
0.000017 (0.000007 - 0.000039) |
0.000054 (0.000037 - 0.000184) | 0.003* | -0.625 |
| IL-13 |
0.000057 (0.000038 - 0.000173) |
0.000047 (0.000034 - 0.000087) | 0.670 | -0.091 |
| TIMP-1 |
0.519388 (0.000000 - 13.457844) |
52.008696 (38.851239 - 80.618044) | < 0.001* | -0.791 |
| TIMP-2 |
0.340405 (0.000000 - 2.521999) |
4.471101 (3.758427 - 5.662756) | 0.002* | -0.665 |
| MMP-3 |
0.130385 (0.000000 - 6.931912) |
81.236149 (0.000000 - 334.057639) | < 0.001* | -0.819 |
| OPG |
0.000148 (0.000045 - 0.000281) |
0.000104 (0.000116 - 0.000447) | 0.224 | -0.259 |
| VEGF |
0.001912 (0.000000 - 0.020470) |
0.019389 (0.011830 - 0.033989) | 0.013 | -0.515 |