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Table 1 Bone Histomorphometry

From: Pinealectomy affects bone mineral density and structure - an experimental study in sheep

 

control

Ovx

 

0 months

6 months

p

0 month

6 months

p

Ct.Wi (μm)

858 ± 225

769 ± 358

0,249

717 ± 244

547 ± 154

0,007

B.Ar/T.Ar (%)

22,6 ± 4,3

21,7 ± 2,7

0,345

20,9 ± 5,0

18,0 ± 1,8

0,014

O.Ar/B.Ar (%)

0,225 ± 0,236

0,209 ± 0,153

0,764

0,072 ± 0,101

0,104 ± 0,116

0,314

O.Pm/B.Pm (%)

1,069 ± 1,092

0,920 ± 0,705

0,643

0,328 ± 0,481

0,504 ± 0,597

0,272

E.Pm/B.Pm (%)

1,952 ± 1,170

1,642 ± 1,036

0,293

1,625 ± 0,867

1,431 ± 0,757

0,419

Oc.Pm/B.Pm (%)

0,033 ± 0,043

0,039 ± 0,062

0,663

0,014 ± 0,033

0,027 ± 0,046

0,289

 

Px

OvxPx

 

0 months

6 months

p

0 month

6 months

p

Ct.Wi (μm)

582 ± 127

637 ± 278

0,341

686 ± 125

552 ± 118

0,000

B.Ar/T.Ar (%)

19,3 ± 3,7

16,8 ± 3,7

0,015

19,7 ± 3,6

17,2 ± 2,857

0,011

O.Ar/B.Ar (%)

0,332 ± 0,323

0,327 ± 0,228

0,946

0,292 ± 0,626

0,303 ± 0,265

0,936

O.Pm/B.Pm (%)

1,545 ± 1,371

1,461 ± 1,029

0,800

1,249 ± 1,687

1,328 ± 1,065

0,846

E.Pm/B.Pm (%)

1,634 ± 1,135

1,920 ± 0,951

0,316

1,322 ± 0,862

2,230 ± 1,446

0,011

Oc.Pm/B.Pm (%)

0,012 ± 0,020

0,052 ± 0,078

0,011

0,021 ± 0,042

0,062 ± 0,068

0,017

  1. Bone histomorphometry of biopsies from iliac crest. Six months after surgery bone area is decreased in all treated groups. Px and OvxPx increases the bone resorption indices including eroded perimeter and osteoclast perimeter indicating stimulated bone resorption.