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Table 2 Effect of dopamine 1/5 receptor agonist SKF 81297 on atrophying (right, casted) and non-atrophying (left, uncasted) C57Bl6 mouse tibialis anterior and medial gastrocnemius muscle mass.

From: Activation of the dopamine 1 and dopamine 5 receptors increase skeletal muscle mass and force production under non-atrophying and atrophying conditions

Parameter Treatment Number of mice Mean Standard Error
Initial body mass (grams) Vehicle 1 8 23.4 0.2
  SKF 81297 8 23.9 0.2
Final body mass (grams) Vehicle 1 8 23.5 0.2
  SKF 81297 8 24.2 0.3
Right Casted Tibialis Anterior (milligrams) Vehicle 1 8 30.9 1.0
  SKF 81297 8 33.3* 0.7
Right Casted Medial Gastrocnemius (milligrams) Vehicle 1 8 32.4 1.1
  SKF 81297 8 36.3* 0.8
Left Uncasted Tibialis Anterior (milligrams) Vehicle 1 8 38.3 0.7
  SKF 81297 8 41.9* 0.7
Left Uncasted Medial Gastrocnemius (milligrams) Vehicle 1 8 40.4 0.7
  SKF 81297 8 43.5* 0.5
  1. * - statistically significant (p < 0.05) versus appropriate vehicle control.