Table 2 Effect of dopamine 1/5 receptor agonist SKF 81297 on atrophying (right, casted) and non-atrophying (left, uncasted) C57Bl6 mouse tibialis anterior and medial gastrocnemius muscle mass.
Parameter | Treatment | Number of mice | Mean | Standard Error |
|---|---|---|---|---|
Initial body mass (grams) | Vehicle 1 | 8 | 23.4 | 0.2 |
| Â | SKF 81297 | 8 | 23.9 | 0.2 |
Final body mass (grams) | Vehicle 1 | 8 | 23.5 | 0.2 |
| Â | SKF 81297 | 8 | 24.2 | 0.3 |
Right Casted Tibialis Anterior (milligrams) | Vehicle 1 | 8 | 30.9 | 1.0 |
| Â | SKF 81297 | 8 | 33.3* | 0.7 |
Right Casted Medial Gastrocnemius (milligrams) | Vehicle 1 | 8 | 32.4 | 1.1 |
| Â | SKF 81297 | 8 | 36.3* | 0.8 |
Left Uncasted Tibialis Anterior (milligrams) | Vehicle 1 | 8 | 38.3 | 0.7 |
| Â | SKF 81297 | 8 | 41.9* | 0.7 |
Left Uncasted Medial Gastrocnemius (milligrams) | Vehicle 1 | 8 | 40.4 | 0.7 |
| Â | SKF 81297 | 8 | 43.5* | 0.5 |