Table 3 Effects of CsA on the mechanical parameters of the lumbar vertebra
From: Effects of cyclosporin-a on rat skeletal biomechanical properties
| Â | Baseline (n = 8) | Control (n = 12) | 1.5 mg CsA (n = 11) | 7.5 mg CsA (n = 9) |
|---|---|---|---|---|
Ultimate force (N) | 143.7 ± 24.4 | 156.9 ± 36.2 | 119.9 ± 34.7* | 113.6 ± 45.8* |
Stiffness (N/mm) | 688.2 ± 209.7 | 756.1 ± 258.6 | 698.7 ± 298.3 | 547.4 ± 250.1 |
Energy absorption (mJ) | 29.8 ± 14.5 | 36.4 ± 16.9 | 24.8 ± 11.7 | 23.9 ± 13.8 |
Ultimate stress (GPa) | 0.017 ± 0.003 | 0.017 ± 0.004 | 0.013 ± 0.003* | 0.011 ± 0.005** |
Young's modulus (Gpa) | 0.488 ± 0.160 | 0.444 ± 0.130 | 0.454 ± 0.213 | 0.333 ± 0.147 |
Energy absorption (mJ/mm3) | 0.81 ± 0.34 | 0.77 ± 0.44 | 0.44 ± 0.24* | 0.34 ± 0.28* |