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Table 3 Genotypes and allelic frequencies of PAI-1 gene polymorphisms between ONFH patients (n = 206) and controls (n = 251)

From: Significant associations of PAI-1 genetic polymorphisms with osteonecrosis of the femoral head

Position Genotype/Allele Controls, n (%) Patients, n (%) OR (95% CI) p
g.-844G/A GG 116(46.2) 67(32.5) 1* 0.011
(rs2227631) GA 97(38.6) 97(47.1) 1.73(1.15-2.61)  
  AA 38(15.1) 42(20.4) 1.91(1.12-3.26)  
  G 329(65.5) 231(56.1) 1* 0.003
  A 173(34.5) 181(43.9) 1.49(1.14-1.95)  
g.-6754G/5G 5G5G 46(18.3) 29(14.1) 1* 0.073
(rs1799889) 4G5G 130(51.8) 95(46.1) 1.16(0.68-1.98)  
  4G4G 75(29.9) 82(39.8) 1.73(0.99-3.04)  
  5G 222(44.2) 153(37.1) 1* 0.030
  4G 280(55.8) 259(62.9) 1.34(1.03-1.75)  
g.10700C/T TT 79(31.5) 45(21.8) 1* 0.013
(rs11178) CT 116(46.2) 93(45.1) 1.41(0.89-2.22)  
  CC 56(22.3) 68(33.0) 2.13(1.28-3.55)  
  T 274(54.6) 183(44.4) 1* 0.002
  C 228(45.4) 229(55.6) 1.50(1.16-1.95)  
  1. *reference category (odds ratio, 1.0)