Table 3 Effects of three months of treatment with either vehicle or PG873637 on sham operated or myocardial infracted rat body mass, fractional area contraction, ejection fraction, systolic area, systolic volume, diastolic area, diastolic volume, scar weight, lung weight, muscle mass and muscle absolute force (Po).

482.8

(6.8)

476.8

(12.4)

480.5

(6.1)

487.4#

(7.6)

63.4

(7.6)

65.2

(6.5)

21.7#

(6.9)

26.0#

(3.2)

68.2

(8.6)

72.6

(4.9)

25.3#

(7.5)

30.5#

(3.6)

18.5

(4.1)

17.7

(3.8)

86.7#

(15.2)

71.8#

(13.1)

0.2

(0.1)

0.2

(0.1)

1.3#

(0.3)

1.0#

(0.3)

50.7

(5.0)

51.1

(5.2)

110.4#

(14.7)

97.3#

(18.5)

0.7

(0.1)

0.7

(0.1)

1.7#

(0.3)

1.5#

(0.3)

NA

NA

0.1

(0.0)

0.1

(0.0)

1.5

(0.1)

1.5

(0.1)

2.8#

(0.9)

2.2#

(1.0)

189.9

(3.7)

228.6*

(6.5)

191.0

(1.9)

230.0*

(5.8)

0.41

(0.01)

0.47*

(0.01)

0.40

(0.01)

0.47*

(0.01)

3348.7

(78.9)

3909.9*

(71.7)

3073.3#

(96.3)

3927.7*

(52.6)

7.16

(0.13)

8.09*

(0.18)

6.41#

(0.24)

8.12*

(0.13)

188.9

(3.2)

222.4*

(7.9)

197.0

(2.6)

222.4*

(7.9)

0.40

(0.01)

0.46*

(0.01)

0.41

(0.01)

0.45*

(0.01)

2033.6

(26.9)

2420.9*

(88.1)

2177.5#

(46.0)

2444.7*

(68.8)

4.38

(0.08)

4.99*

(0.15)

4.53

(0.09)

5.06*

(0.14)