Days of work missed. Days of work missed per week at the beginning and end of trials as assessed by the question "How many days in the past week did you miss work, including housework, because of fibromyalgia?" from the Fibromyalgia Impact Questionnaire (FIQ). Data are presented as a comparison of 'state' and 'improvement' responders; 'non-responders' are neither state nor improvement responders; 'double responders' are both. ** p < 0.01, *** p < 0.001, **** p < 0.0001, NS - no significant difference, SD - standard deviation. FIQ data were not available for trial 105, the only trial with a 150 mg pregabalin group. Therefore no data for participants treated with 150 mg pregabalin are presented here.