Figure 4

Treatment with raloxifene did not increase uterine weight. Scatter plots showing the uterine weights in mice with CIA treated with raloxifene (60 μg/day), E2 (1 μg/day) or vehicle Miglyol812 (100 μl/day) from day 22 to day 56 after immunization, and terminated on day 73, n = 11-15 in each group. Lines represent medians. Kruskall-Wallis test with post hoc comparison was used, **P < 0.01, ***P < 0.001.