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Table 2 Effects of a 16-week exercise program on clinical and laboratorial parameters related to inflammation, muscle damage, pain, disease activity, and quality of life in a 7-year-old patient with juvenile dermatomyositis (JDM) and in her unaffected monozygotic twin sister.

From: Responsiveness to exercise training in juvenile dermatomyositis: a twin case study

  Healthy twin JDM twin
Variable Pre Post Pre Post
CMAS 49 49 46 46
MMT 80 80 80 80
CHAQ 0 0 0 0
VAS (Physician's scale) 0 0 0 0
VAS (Parents' scale) 0 0 0 0
PGA 0 0 0 0
PaGA 0 0 0 0
CK (IU/L) 152 201 155 218
LDH (IU/L) 213 166 171 183
Aldolase (IU/L) 6 6 7 7
ESR (mm/hr) 12 15 20 20
C-reactive protein (mg/L) 0.32 0.79 1.73 0.70
  1. Abbreviations: CMAS = Childhood Muscle Assessment Scale; MMT = Manual Muscle Test; CHAQ = Childhood Health Assessment Questionnaire; VAS = Visual Analogic Score; PGA = Physician Global Assessment of Disease Activity; PaGA = Parents/Patient Global Assessment of Disease Activity; CK = Creatine kinase; LDH = Lactate Dehydrogenase; ESR = Erythrocyte Sedimentation Rate. Normal range for CK, LDH, aldolase, ESR and C-reactive protein are 24-192 IU/L, 141-237 IU/L, 1-7.4 IU/L, 0-20 mm/1st hr, 0-5 mg/L, respectively. Score range for CMAS, MMT, CHAQ, PGA and PaGA are 0-52, 0-80, 0-3, 0-10, 0-10, respectively.