Table 1 Characteristics of patients with and without anti-CCP antibodie
| Â | anti-CCP positive (n = 48) | anti-CCP negative (n = 44) | P value |
|---|---|---|---|
Female (n (%)) | 28 (58.3%) | 22 (50.0%) | 0.42* |
Age at inclusion, years (mean ± standard deviation) | 56.6 ± 15.0 | 61.5 ± 14.7 | 0.12** |
Ethnicity - Caucasian (n (%)) | 38 (79.2%) | 39 (88.6%) | 0.22* |
Smoking status - Current/ever smoked (n (%)) | 31 (64.6%) | 28 (63.6%) | 0.92* |
Symptom duration, days (mean ± standard deviation) | 49.3 ± 20.2 | 56.4 ± 22.3 | 0.12** |
Mode of onset (n (%)) | Â | Â | Â |
Acute | 25 (52.1%) | 25 (56.8%) | 0.65* |
Insidious | 21 (43.8%) | 18 (40.9%) | Â |
Unspecified | 2 (4.16%) | 1 (2.27%) | Â |
Morning Stiffness | Â | Â | Â |
Duration, mins (mean ± standard deviation) | 93.3 ± 89.5 | 123.8 ± 92.8 | 0.11** |
No. patients ≥60 mins (n (%)) | 28 (58.3%) | 32 (72.7%) | 0.15* |
Symmetry (n (%)) | 35 (72.9%) | 33 (75.0%) | 0.82* |
Hand joint involvement (n (%)) | 43 (89.6%) | 41 (93.2%) | 0.54* |
≥ 3 joint areas involved (n (%)) | 31 (64.6%) | 30 (68.2%) | 0.63* |
Nodules (n (%)) | 2 (4.17%) | 1 (2.27%) | 0.61* |
Erosions (n (%)) | 1 (2.08%) | 2 (4.54%) | 0.51* |
Rheumatoid factor positive (n (%)) | 40 (83.3%) | 5 (11.4%) | < 0.001* |
1987 ACR criteria for RA | Â | Â | Â |
Total No. (mean ± standard deviation) | 3.73 ± 1.09 | 3.23 ± 1.14 | 0.03** |
No. fulfilling ≥ 4 criteria (n (%)) | 28 (58.3%) | 16 (36.4%) | 0.04* |
Tender joint count (max 68) (mean ± standard deviation) | 8.33 ± 7.80 | 9.66 ± 8.90 | 0.45** |
Swollen joint count (max 66) (mean ± standard deviation) | 5.79 ± 4.51 | 7.07 ± 5.83 | 0.25** |
ESR mm/hr (mean ± standard deviation) | 32.3 ± 20.1 | 38.7 ± 29.3 | 0.23** |
CRP mg/L (mean ± standard deviation) | 29.0 ± 27.0 | 31.4 ± 30.8 | 0.70** |