From: Atypical depression is more common than melancholic in fibromyalgia: an observational cohort study
ADE CRITERIA | No MDD | ADE | MDE | ?2 | ADE v. MDE (n = 67) | |
---|---|---|---|---|---|---|
 | (A: n = 9) | (B: n = 40) | (C: n = 27) | P value | OR | P Value |
Mood reactivity | 4/9 | 40/40 | 20/27 | TS < 0.001 | 1.0 | |
 | 44.4% | 100% | 74.1% | a-b < 0.001 | (Perfect Predictability) | |
 |  |  |  | a-c 0.13 |  |  |
 |  |  |  | b-c 0.001 |  |  |
Significant weight gain or | 0/9 | 27/40 | 10/27 | TS < 0.001 | 3.53 | 0.02 |
increased appetite | 0% | 67.5% | 37% | a-b < 0.001 | Â | Â |
 |  |  |  | a-c 0.04 |  |  |
 |  |  |  | b-c 0.02 |  |  |
Hypersomnia | 0/9 | 14/40 | 5/27 | TS 0.06 | 2.37 | 0.15 |
 | 0% | 35% | 18.5% | a-b 0.05 |  |  |
 |  |  |  | a-c 0.30 |  |  |
 |  |  |  | b-c 0.18 |  |  |
Leaden paralysis (i.e., heavy, | 4/9 | 40/40 | 26/27 | TS < 0.001 | 1.0 | |
leaden feelings in arms or legs) | 44.4% | 100% | 96.3% | a-b < 0.001 | (Perfect Predictability) | |
 |  |  |  | a-c 0.002 |  |  |
 |  |  |  | b-c 0.40 |  |  |
Long-standing pattern of | 0/9 | 27/38 | 13/27 | TS < 0.001 | 2.64 | 0.06 |
interpersonal rejection sensitivity | 0% | 71.1% | 48.1% | a-b < 0.001 | Â | Â |
 |  |  |  | a-c 0.01 |  |  |
 |  |  |  | b-c 0.07 |  |  |
Criteria not met for MDE during | 9/9 | 40/40 | 0/27 | TS < 0.001 | 0.007 | 0.007 |
the same episode | 100% | 100% | 0% | a-b 1.00 | Â | Â |
 |  |  |  | a-c < 0.001 |  |  |
 |  |  |  | b-c < 0.001 |  |  |