Table 1 Runx2, Alp and Ocn expressions in day 3 samples (fold-change in gene expression)
(A) Runx2 expression in day 3 samples (fold-change in gene expression) | ||
|---|---|---|
0 μM SB431542 | 5 μM SB431542 | |
no BMP-2/TGF-β1 | 1.00 (0.11) | 1.77 (0.15) |
50 ng/ml BMP-2 | 1.62 (0.10) | 3.59 (0.34) |
5 ng/ml TGF-β1 | 0.54 (0.10) | 2.01 (0.09) |
50 ng/ml BMP-2, 5 ng/ml TGF-β1 | 0.56 (0.12) | 2.05 (0.23) |
(B) Alp expression in day 3 samples (fold-change in gene expression) | ||
0 μM SB431542 | 5 μM SB431542 | |
no BMP-2/TGF-β1 | 1.00 (0.13) | 3.51 (0.25) |
50 ng/ml BMP-2 | 5.50 (1.25) | 11.05 (0.29) |
5 ng/ml TGF-β1 | 0.15 (0.04) | 0.92 (0.08) |
50 ng/ml BMP-2, 5 ng/ml TGF-β1 | 0.27 (0.05) | 3.47 (0.38) |
(C) Ocn expression in day 10 samples (fold-change in gene expression) | ||
0 μM SB431542 | 5 μM SB431542 | |
no BMP-2/TGF-β1 | 1.00 (0.06) | 1.45 (0.25) |
50 ng/ml BMP-2 | 4.11 (0.28) | 5.18 (0.34) |
5 ng/ml TGF-β1 | 0.06 (0.01) | 0.70 (0.03) |
50 ng/ml BMP-2, 5 ng/ml TGF-β1 | 0.69 (0.06) | 3.72 (0.06) |