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Table 6 Quality assessment of the grade of evidence of the observational studies comparing TKA with – and without prior HTO

From: Total knee arthroplasty after high tibial osteotomy. A systematic review

   Quality assessment     Summary of findings
      No of knees Effects   
No of studies Design Quality Consistency Directness HTO no HTO   Quality Importance
Range of motion (6)
  observational no serious limitations no important inconsistency direct 251 251 4/6 studies no difference low critical
Knee clinical scores (9)
  observational no serious limitations no important inconsistency direct     low critical
HSS (5/9)      212 212 5/5 studies no difference   
KSS (5/9)      175 176 4/5 study no difference   
other (3/9)      106 105 2/3 studies no difference   
Revision surgery because of (a)septic loosening (8)
  observational no serious limitations no important inconsistency direct 298 296 8/8 studies no difference low critical