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Table 1 Baseline characteristics of patients treated with pamidronate iv or oral bisphosphonates

From: Treatment with intravenous pamidronate is a good alternative in case of gastrointestinal side effects or contraindications for oral bisphosphonates

Variables

 

Oral Bisphosphonates n = 31

Pamidronate n = 30

p value

Duration of treatment (years)

mean (range)

4.2 (4.9)

4.3 (4.8)

0.914

Age (years)

mean (SD)

62 (13.9)

67 (9.6)

0.132

Gender (female)

n (%)

24 (77)

24 (80)

0.527

Age at menopause (years)

mean (SD)

48 (4.6)

46 (5.3)

0.178

BMI (kg/m2)

mean (SD)

24 (4.7)

25 (4.5)

0.636

Number of patients with at least 1 clinical fracture

n (%)

9 (29)

5 (17)

0.251

Familial fractures

n (%)

12 (36)

11 (37)

0.516

Dietary calcium intake (mg/day)

mean (SD)

925 (366)

838 (241)

0.293

Calcium supplementation daily dose (mg)

n (%)

12

9

0.678

 

mean (SD)

541 (144)

610 (334)

0.531

Treatment with prednisone daily dose (mg)

n (%)

6 (18)

5 (17)

0.835

 

mean (SD)

10 (4.2)

11.5 (6)

0.638

T score spine

mean (SD)

-2.39 (1.55)

-2.58 (0.89)

0.562

T score hip

mean (SD)

-1.85 (1.13)

-1.79 (1.03)

0.816

Serum 25(OH) D levels (nmol/l)

mean (SD)

70 (31)

62 (29)

0.313

Serum calcium levels (mmol/l)

mean (SD)

2.38 (0.1)

2.39 (0.1)

0.678

Serum albumin levels (g/l)

mean (SD)

41 (9)

39 (4)

0.356

  1. At baseline there are no significant differences between the oral bisphosphonates group and the pamidronate iv group