BMC Musculoskeletal Disorders

Table 3 Agreement between disease activity states at baseline and three month according to various indices, expressed as percentages and κ values.

From: Disease activity level, remission and response in established rheumatoid arthritis: Performance of various criteria sets in an observational cohort, treated with anti-TNF agents

Baseline
Valid N		DAS28 modified cut off		SDAI		CDAI
		1657		1657		1681
Reference criterion	Valid N	%	κ	%	κ	%	κ
*High disease activity*
DAS28 original	1657	52/35	0,73	60/27	0,69	61/24	0,65
DAS28 modified cut off	1657			50/31	0,62	51/27	0,54
SDAI	1672					67/26	0,83
*Moderate disease activity*
DAS28 original	1657	29/55	0,66	23/61	0,63	20/62	0,58
DAS28 modified cut off	1657			25/52	0,52	21/53	0,42
SDAI	1672					24/69	0,80
*Low disease activity*
DAS28 original	1657	2.7/94	0,64	1.3/96	0,55	1.3/96	0,54
DAS28 modified cut off	1657			1.8/94	0,46	1.6/94	0,41
SDAI	1672					1.7/97	0,81
*Remission*
DAS28 original	1657	0.6/99	0,91	0.1/99	0,15	0.1/99	0,15
DAS28 modified cut off	1657			0.1/99	0,18	0.1/99	0,18
SDAI	1672					0/100	1,00
3 month
*Valid N*		*1214*		*1224*		*1232*
*High disease activity*
DAS28 original	1206	12/83	0,82	13/79	0,72	13/78	0.69
DAS28 modified cut off	1214			11/82	0,72	11/80	0.67
SDAI	1224					15/80	0,83
*Moderate disease activity*
DAS28 original	1206	34/50	0,67	32/46	0,55	30/45	0,49
DAS28 modified cut off	1214			29/50	0,56	26/49	0,47
SDAI	1224					35/55	0,79
*Low disease activity*
DAS28 original	1206	38/51	0,77	33/53	0,71	32/52	0,67
DAS28 modified cut off	1214			39/47	0,71	37/46	0,66
SDAI	1224					40/55	0,88
*Remission*
DAS28 original	1206	18/77	0,87	7.7/77	0,42	7.3/76	0,40
DAS28 modified cut off	1214			7.1/80	0,47	6.7/80	0,44
SDAI	1224					7.5/91	0,91

Percentages denote positive agreement/negative agreement, i.e. per cent patients achieving both compared activity states/per cent patients achieving neither.

Back to article page

ISSN: 1471-2474

Contact us

Submission enquiries: bmcmusculoskeletaldisorders@biomedcentral.com
General enquiries: ORSupport@springernature.com