The number of articular elements showing pathological changes stratified by cartilage disease score (CDS). CDS is a summation of all compartmental cartilage disease severity and lesion size scores across the entire knee. These scores were then categorized as mild, moderate and severe based on the methodology described in Table 1. The number of articular elements involved is categorized as 0-1 element, 2-3 elements and 4-5 elements. The y-axis indicates the percentage of patients in that CDS grouping with evidence of pathological change in articular elements on MRI. The articular elements included in this figure are osteophytosis, subchondral sclerosis, bone marrow lesions, joint effusion and synovitis. The trend of increasing number articular elements with increasing CDS is statistically significant (p-value for trend < 0.0001).