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Table 4 Associations between weight loss or subcutaneous fat change and synovitis progression

From: Effect of weight loss on knee joint synovitis over 48 months and mediation by subcutaneous fat around the knee: data from the Osteoarthritis Initiative

 

Weight loss, SD

AjSCF decrease, SDa

OR (95% CI)

P-value

OR (95% CI)

P-value

All (n = 234)

 Effusion-synovitis

0.61 (0.44, 0.83)

0.002

0.56 (0.40, 0.79)

0.001

 Hoffa-synovitis

1.47 (1.05, 2.04)

0.024

1.48 (1.02, 2.13)

0.038

Men (n = 72)

 Effusion-synovitis

0.40 (0.20, 0.81)

0.011

0.15 (0.05, 0.50)

0.002

 Hoffa-synovitis

2.08 (1.01, 4.29)

0.048

1.80 (0.64, 5.12)

0.267

Women (n = 162)

 Effusion-synovitis

0.69 (0.48, 0.98)

0.039

0.69 (0.49, 0.99)

0.042

 Hoffa-synovitis

1.33 (0.90, 1.95)

0.149

1.47 (0.99, 2.19)

0.059

  1. Logistic regression models are adjusted for age, sex, baseline BMI, PASE, and ajSCF. Statistically significant p-values are in bold
  2. a 5 missing average joint-adjacent subcutaneous fat measurements (AjSCF) due to missing MRI data (3 anterior SCF, 4 medial and lateral SCF measurements each)
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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