Table 1 Definition of comorbidity variables
From: Clinical phenotypes of comorbidities in end-stage knee osteoarthritis: a cluster analysis
Comorbidities | Definition |
|---|---|
Obesity | BMI ≥ 28 kg/m2 |
Hypertension | Systolic blood pressure ≥ 140 mmHg and or diastolic blood pressure ≥ 90 mmHg or history of hypertension |
Type 2 diabetes | Fasting blood glucose ≥ 7.0 mmol/L or HbA1c ≥ 6.5 or history of type 2 diabetes |
Stroke | Pre-existing diagnosis of stroke |
Hyperlipidemia | TC ≥ 6.22 mmol/L or TG ≥ 2.26 mmol/L |
Sleep disorder | Insomnia ≥ 3 times per week for more than 1 month |
Hyperuricemia | Fasting blood uric acid ≥ 420 umol/L or previous history of hyperuricemia |
Coronary artery disease | Prior history of angina pectoris and/or myocardial infarction or ECG-confirmed coronary artery disease |
Depression | D(HADS) ≧ 11 or previous diagnosis of depression |
Anxiety | A(HADS) ≧ 11 or previous diagnosis of anxiety disorder |
Chronic kidney disease | Blood creatinine ≥ 133umol/L or previous history of chronic kidney disease |
Liver disease | Hepatic steatosis or cirrhosis or abnormal liver enzyme levels (ALT ≥ 60 U/L) |
Rheumatoid arthritis | Previously diagnosed rheumatoid arthritis (excluding simple rheumatoid arthritis) |