Table 4 Phenotypes with causal relationships with hand OA

Treatment/medication code: diclofenac sodium + misoprostol

0.471

-0.711

9.84E-04

Diagnoses - main ICD10: M47 Spondylosis

0.385

-0.668

2.62E-03

Pain type(s) experienced in last month: Hip pain

0.345

0.661

1.90E-03

Leg pain on walking

0.470

0.711

5.03E-04

Medication for pain relief, constipation, heartburn: Omeprazole (e.g. Zanprol)

0.347

0.714

1.54E-04

Mineral and other dietary supplements: Glucosamine

0.435

0.730

1.28E-05

Treatment/medication code: diclofenac

0.428

0.870

2.69E-04

Shoulder lesions

0.393

0.922

1.88E-62

Diagnoses - main ICD10: M75 Shoulder lesions

0.394

0.922

1.11E-62