From: Association of sarcopenia with osteoporosis in Chinese patients with type 2 diabetes
Variables | Men(n = 447) | Women(n = 231) | ||||
---|---|---|---|---|---|---|
Sarcopenia (n = 84) | Non-sarcopenia (n = 363) | p | Sarcopenia (n = 34) | Non-sarcopenia (n = 197) | p | |
Age(y) | 63.71 ± 14.51 | 54.53 ± 12.77 | 0.03 | 64.59 ± 10.69 | 61.31 ± 11.79 | 0.12 |
Education level(%) | 0.39 | 0.17 | ||||
Junior high school or below | 76.2%(64) | 71.6%(260) | 97.1%(33) | 89.8%(177) | ||
High school and above | 23.8%(20) | 28.4%(103) | 2.9%(1) | 10.2%(20) | ||
Drinking (%) | 52.4%(44) | 55.6%(202) | 0.58 | 2.9%(1) | 5.1%(10) | 0.58 |
Smoking (%) | 67.9%(57) | 58.4%(212) | 0.11 | 2.9%(1) | 0.5%(1) | 0.15 |
Stroke (%) | 20.2%(17) | 7.7%(28) | < 0.01 | 11.8%(4) | 12.2%(24) | 0.94 |
Coronary Heart Disease (%) | 19.0%(16) | 7.2%(26) | < 0.01 | 2.9%(1) | 7.6%(15) | 0.32 |
BMD(SD) | ||||||
L1-L4 | -0.71 ± 1.76 | -0.33 ± 1.43 | 0.18 | -1.88 ± 1.36 | -1.34 ± 1.54 | 0.05 |
femoral neck | -1.67 ± 1.08 | -0.79 ± 1.11 | 0.95 | -2.02 ± 1.06 | -1.36 ± 1.15 | < 0.01 |
Hip | -1.31 ± 1.05 | -0.57 ± 1.03 | 0.93 | -1.73 ± 1.19 | -0.87 ± 1.26 | < 0.01 |
BMI | 21.38 ± 2.83 | 24.33 ± 3.26 | 0.20 | 20.45 ± 2.89 | 23.72 ± 3.13 | < 0.01 |
WC (cm) | 85.96 ± 9.79 | 91.66 ± 8.99 | 0.32 | 84.10 ± 8.34 | 90.16 ± 9.33 | < 0.01 |
HC (cm) | 90.00 ± 7.93 | 95.22 ± 6.16 | < 0.01 | 90.24 ± 5.73 | 94.19 ± 7.09 | < 0.01 |
SBP (mmHg) | 142.28 ± 21.96 | 131.29 ± 18.72 | 0.05 | 141.44 ± 22.76 | 136.56 ± 19.69 | 0.24 |
DBP(mmHg) | 78.53 ± 12.31 | 76.91 ± 11.29 | 0.22 | 77.33 ± 10.06 | 75.69 ± 9.47 | 0.40 |
HbA1c(%) | 9.49 ± 2.55 | 9.74 ± 2.39 | 0.99 | 9.29 ± 21.50 | 9.27 ± 2.20 | 0.96 |
25(OH)D (nmol/L) | 49.89 ± 20.93 | 59.42 ± 21.19 | 0.94 | 51.92 ± 19.70 | 56.19 ± 19.35 | 0.25 |
Estradiol(pmol/L) | 201.39 ± 89.96 | 170.43 ± 66.34 | < 0.01 | 143.18 ± 148.75 | 141.92 ± 127.77 | 0.96 |
Testosterone(nmol/L) | 10.14 ± 4.95 | 10.98 ± 4.34 | 0.35 | 0.90 ± 0.59 | 1.01 ± 0.97 | 0.54 |
IGF-1 (ng/mL) | 165.78 ± 116.71 | 163.36 ± 55.84 | 0.01 | 153.90 ± 51.01 | 129.42 ± 56.57 | 0.21 |
ASM (kg) | 17.59 ± 1.98 | 23.21 ± 3.07 | < 0.01 | 12.15 ± 1.29 | 16.51 ± 2.18 | < 0.01 |
SMI (kg/m2) | 6.36 ± 0.55 | 8.09 ± 0.94 | < 0.01 | 4.93 ± 0.41 | 6.67 ± 0.77 | < 0.01 |
Grip(kg) | 22.62 ± 7.41 | 36.06 ± 7.98 | 0.32 | 14.40 ± 5.14 | 20.60 ± 5.45 | < 0.01 |
Gait speed(m/s) | 0.81 ± 0.24 | 1.08 ± 0.20 | 0.12 | 0.82 ± 0.17 | 0.92 ± 0.19 | 0.02 |
Osteopenia (%) | 39.5%(32) | 32.2%(112) | 0.20 | 37.5%(12) | 36.5%(69) | 0.91 |
Osteoporosis (%) | 30.9%(25) | 8.6%(30) | < 0.01 | 46.9%(15) | 33.9%(64) | 0.15 |