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Table 6 Correlation between 7-joint ultrasound score and different parameters in RA

From: Osteopontin, osteoprotegerin and musculoskeletal ultrasound findings in first-degree relatives of rheumatoid arthritis: potential markers of preclinical disease

  

US7 score

  

Synovitis GS

Synovitis PD

Tenosynovitis GS

Tenosynovitis PD

US erosions

Total US scores

Disease duration

rs

-0.150

-0.089

0.101

0.007

0.535*

0.145

P

0.529

0.709

0.671

0.976

0.015*

0.542

DAS28

rs

0.024

-0.265

0.175

-0.239

-0.077

-0.059

P

0.922

0.259

0.534

0.309

0.747

0.805

HAQ score

rs

-0.210

0.005

0.057

-0.013

0.334

0.077

P

0.373

0.982

0.812

0.955

0.151

0.746

PGA

rs

-0.349

-0.111

0.208

0.321

-0.082

-0.172

P

0.132

0.640

0.379

0.168

0.731

0.469

Pain –VAS

rs

-0.349

-0.111

0.208

0.321

-0.082

-0.172

P

0.132

0.640

0.379

0.168

0.731

0.469

ESR 1st hr

rs

0.015

-0.090

-0.087

0.136

-0.336

-0.024

P

0.951

0.707

0.717

0.569

0.147

0.919

CRP

rs

-0.241

-0.065

-0.369

-0.306

-0.093

-0.206

P

0.305

0.784

0.110

0.189

0.695

0.385

RF

rs

0.176

0.365

0.525*

0.346

0.377

0.443

P

0.459

0.114

0.017*

0.135

0.101

0.051

ACPA

rs

0.459*

0.627*

0.675*

0.554*

0.402

0.666*

P

0.042*

0.003*

0.001*

0.011*

0.079

0.001*

Serum OPN

rs

0.323

-0.003

-0.092

0.169

0.179

0.342

P

0.165

0.991

0.699

0.475

0.450

0.141

Serum OPG

rs

0.512*

0.323

0.160

0.136

0.138

0.509*

P

0.021*

0.165

0.500

0.569

0.562

0.022*

  1. rs: Spearman coefficient, *: Statistically significant at p ≤ 0.05
  2. US7: 7-joint ultrasound score; GS: Grayscale; PD: power Doppler; DAS: disease activity score; HAQ: health assessment questionnaire; PGA: Patient global assessment; VAS: Visual Analogue Scale; ESR: erythrocyte sedimentation rate; CRP: c-reactive protein; RF: rheumatoid factor; ACPA: anti-citrullinated protein antibodies; OPN: Osteopontin; OPG: Osteoprotegerin