Table 4 Relation between articular manifestations and different parameters in first degree relatives (n = 25)

ESR 1st hr(10 mm/hr)

Min. – Max.

5.0–20.0

9.0–45.0

0.003^*

Mean ± SD.

9.82 ± 4.13

27.88 ± 11.22

Median

8.0

27.50

CRP (< 3 mg/L)

Min. – Max.

0.82–13.0

2.88–19.0

0.003^*

Mean ± SD.

3.93 ± 3.58

10.36 ± 5.21

Median

2.78

9.87

RF (< 15.9 IU/ml)

Negative

17 (100)

8 (100)

-

Positive

0 (0)

0 (0)

Min. – Max.

4.90–12.70

4.80–12.50

0.137

Mean ± SD.

8.55 ± 2.49

9.52 ± 1.54

Median

9.18

9.19

ACPA (< 20 U/ml)

Negative

17 (100)

8 (100)

-

Positive

0 (0)

0 (0)

Min. – Max.

7.40–17.0

5.0–17.60

0.560

Mean ± SD.

10.44 ± 3.31

11.35 ± 3.55

Median

9.80

11.20

Serum OPN (ng/ml)

Min. – Max.

1.0–2.40

0.90–5.80

0.620

Mean ± SD.

1.70 ± 0.55

2.09 ± 1.19

Median

1.60

1.80

Serum OPG (pg/ml)

Min. – Max.

0.0–27.20

0.0–334.10

0.314

Mean ± SD.

8.44 ± 9.67

51.55 ± 114.68

Median

1.50

14.25