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Table 2 Changes in VAS, FROM, TG, VMO Thickness, 6MWT, TUG and WOMAC (total and subscales) between the groups

From: A controlled randomized trial with a 12-week follow-up investigating the effects of medium-frequency neuromuscular electrical stimulation on pain, VMO thickness, and functionality in patients with knee osteoarthritis

 

NMES Group

(n = 25)

Mean (SD)

Exs Group

(n = 25)

Mean (SD)

NMES + Exs Group

(n = 25)

Mean (SD)

P value

(P ≤ 0.05)

VAS (0–10)

 pre-intervention

5.10(1.37)

5.17(1.01)

5.47(1.32)

0.615c

 post-intervention

3.18(1.04)

3.66(0.97)

2.94(1.34)

0.226c

 after 12 weeks

1.78(0.89)

2.84(0.80)

1.93(1.27)

0.022a

 P value

< 0.0001e

< 0.0001e

< 0.0001e

 

FROM (degree)

 pre-intervention

115.26(3.09)

110.32(3.27)

120.51(4.22)

0.79g

 post-intervention

117.13(2.02)

110.50(2.59)

123.35(3.81)

< 0.0001b

 after 12 weeks

118.60(2.59)

112.26(2.14)

128.50(2.25)

< 0.0001b

 P value

< 0.0001d

0.397f

< 0.0001d

 

TG (cm)

 pre-intervention

49.31(2.23)

48.22(2.63)

50.25(2.43)

0.316g

 post-intervention

50.45(2.95)

47.55(2.95)

52.80(1.95)

< 0.004b

 after 12 weeks

52.15(2.26)

48.35(2.26)

54.25(2.16)

< 0.0001b

 P value

< 0.0001d

0.023d

< 0.0001d

 

VMO Thickness (mm)

 pre-intervention

16.01(0.43)

15.60(0.73)

15.01(0.63)

0.361g

 post-intervention

17.22(0.59)

15.72(0.39)

16.42(0.19)

 < 0.003b

 after 12 weeks

17.71(0.62)

15.81(0.56)

18.17(0.32)

 < 0.0001b

 P value

< 0.0001d

0.076f

< 0.0001d

 

TUG (second)

 pre-intervention

9.71(0.68)

9.98(0.65)

9.87(0.58)

0.603c

 post-intervention

8.60(0.70)

9.42(0.26)

8.91(0.23)

 < 0.0001a

 after 12 weeks

7.72(0.63)

9.01(0.31)

8.22(0.65)

 < 0.0001a

 P value

< 0.0001e

< 0.0001e

< 0.0001e

 

6MWT(m)

 pre-intervention

442.36(47.14)

437.64(51.50)

432.65(54.41)

0.842c

 post-intervention

523.19(59.05)

470.60(59.38)

511.53(45.21)

0.038a

 after 12 weeks

548.93(36.65)

493.23(62.30)

526.20(47.70)

0.029a

 P value

< 0.0001e

< 0.0001e

< 0.0001e

 

WOMAC pain subscale

 pre-intervention

9.20(0.78)

9.73(0.18)

9.34(0.64)

0.688g

 post-intervention

6.13(0.68)

6.43(0.65)

6.24(0.71)

0.061g

 after 12 weeks

5.16(0.96)

6.56(0.98)

3.98(0.51)

 

 P value

< 0.0001f

< 0.0001f

< 0.0001f

0.003b

WOMAC stiffness subscale

 pre-intervention

3.84(1.17)

3.82(0.81)

3.81(0.98)

0.097c

 post-intervention

2.94(0.85)

2.87(0.52)

2.47(0.87)

< 0.0001a

 after 12 weeks

1.93(0.97)

2.03(0.97)

1.40(1.05)

< 0.0001a

 P value

< 0.0001e

< 0.0001e

< 0.0001e

 

WOMAC function subscale

 pre-intervention

33.98(2.93)

34.86(2.96)

35.25(2.57)

0.646g

 post-intervention

27.46(2.49)

28.50(2.87)

28.32(1.92)

0.231g

 after 12 weeks

21.43(1.32)

21.56(1.29)

22.13(1.75)

0.017b

 P value

< 0.0001f

< 0.0001f

< 0.0001f

 

WOMAC total score

 pre-intervention

45.96(3.32)

48.46(3.60)

46.87(4.04)

0.720g

 post-intervention

37.53(4.12)

39.48(2.16)

38.67(3.27)

0.071g

 after 12 weeks

26.96(1.84)

29.26(2.20)

27.73(2.98)

0.007b

 P value

< 0.0001f

< 0.0001f

< 0.0001f

 
  1. Abbreviation: VAS Visual Analog Scale, FROM Flexion Range of Motion, TG Thigh Girth, VMO Vastus Medialis Oblique, TUG Timed Up and Go, 6MWT Six-Minute Walk, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index
  2. aSignificant difference post intervention among groups based on ANOVA
  3. bSignificant difference post intervention among groups based on Kruskal–Wallis test
  4. cNon-significant difference in the baseline among groups based on ANOVA
  5. dSignificant difference based on Friedman test
  6. eSignificant difference based on repeated measure ANOVA
  7. fNon-significant difference based on Friedman test
  8. gNon-significant difference in the baseline based on Kruskal–Wallis test