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Table 2 Genes the expression levels of which differed between untreated patients and untreated controls (78 genes)

From: Gene expression profiling in patients with polymyalgia rheumatica before and after symptom-abolishing glucocorticoid treatment

Gene symbol

Gene name

Probe set(s)

FDa

p

BDNF

brain-derived neurotrophic factor

244503_at

+1.8

0.016

ETS2

v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

201328_at

+1.8

0.007

SVIP

small VCP/p97-interacting protein

230285_at

+1.7

0.002

SH3RF2

SH3 domain containing ring finger 2

228892_at

+1.6

0.004

TM4SF18

transmembrane 4 L six family member 18

230061_at

+1.5

0.007

TMTC1

transmembrane and tetratricopeptide repeat containing 1

226322_at

226931_at

+1.5

+1.6

0.003

<0.001

TMEM18

transmembrane protein 18

225489_at

+1.5

0.008

N4BP2L1

NEDD4 binding protein 2-like 1

213375_s_at

+1.5

0.019

FMO2

flavin containing monooxygenase 2 (non-functional)

228268_at

+1.5

0.002

RPL37

ribosomal protein L37

224763_at

+1.5

<0.001

CTDSP2

CTD (carboxy-terminal domain. RNA polymerase II. polypeptide A) small phosphatase 2

238999_at

+1.4

0.048

RASL10B

RAS-like. Family 10. member B

235488_at

+1.4

0.012

SMG1P1

nuclear pore complex interacting protein-like

231989_s_at

+1.4

0.008

ZNF331

zinc finger protein 331

219228_at

+1.4

<0.001

FAM184B

family with sequence similarity 184. member B

235288_at

+1.4

0.013

LOC100507303

uncharacterized LOC100507303

228049_x_at

+1.4

0.019

NCKIPSD

NCK interacting protein with SH3 domain

218697_at

+1.4

<0.001

ECHDC3

enoyl CoA hydratase domain containing 3

219298_at

+1.3

0.049

RNF114

ring finger protein 114

200867_at

200868_s_at

211678_s_at

+1.3

+1.3

+1.2

0.006

0.023

0.018

TMPO

thymopoietin

224944_at

+1.3

0.002

RERE

arginine-glutamic acid dipeptide (RE) repeats

200940_s_at

+1.3

0.003

TUBD1

tubulin. Delta 1

231853_at

+1.3

0.003

MARK4

MAP/microtubule affinity-regulating kinase 4

55065_at

+1.3

0.005

ZNF195

zinc finger protein 195

204234_s_at

+1.3

0.003

PCF11

PCF11. cleavage and polyadenylation factor subunit. Homolog (S. cerevisiae)

203378_at

+1.3

0.007

DFFA

DNA fragmentation factor. 45 kDa. alpha polypeptide

226116_at

+1.3

0.010

PSPC1

paraspeckle component 1

218371_s_at

+1.3

0.007

RBBP6

retinoblastoma binding protein 6

212783_at

+1.3

0.004

EIF4B

eukaryotic translation initiation factor 4B

211937_at

+1.3

0.017

NPM1

nucleophosmin (nucleolar phosphoprotein B23. numatrin)

221691_x_at

+1.3

0.011

RSBN1

round spermatid basic protein 1

213694_at

+1.2

0.003

PSIP1

PC4 and SFRS1 interacting protein 1

209337_at

+1.2

0.010

EIF3G

eukaryotic translation initiation factor 3. subunit G

208887_at

+1.2

0.006

COL4A3BP

collagen. Type IV. alpha 3 (Goodpasture antigen) binding protein

219625_s_at

223465_at

+1.2

+1.2

0.003

0.029

PCID2

PCI domain containing 2

219940_s_at

+1.2

0.003

PXDC1

PX domain containing 1

212923_s_at

+1.2

0.042

BCKDHA

branched chain keto acid dehydrogenase E1, alpha polypeptide

202331_at

+1.2

0.024

AKR7A2

aldo-keto reductase family 7, member A2

202139_at

+1.2

0.010

MRPS2

mitochondrial ribosomal protein S2

218001_at

+1.2

0.018

RORA

RAR-related orphan receptor A

226682_at

+1.2

0.049

RPL36AL

ribosomal protein L36a-like

207585_s_at

+1.2

0.011

TFRC

transferrin receptor (p90, CD71)

208691_at

–3.0

0.004

SFRP4

secreted frizzled-related protein 4

204051_s_at

204052_s_at

−2.9

0.001

0.002

NOV

nephroblastoma overexpressed

214321_at

−2.0

0.037

PAQR9

progestin and adipoQ receptor family member IX

1558322_a_at

−2.0

<0.001

C2orf88

chromosome 2 open reading frame 88

228195_at

−1.9

0.011

FAM69A

family with sequence similarity 69, member A

213689_x_at

−1.8

0.001

TP53INP2

tumor protein p53 inducible nuclear protein 2

224836_at

−1.8

−1.9

<0.001

0.002

SH3KBP1

SH3-domain kinase binding protein 1

1554168_a_at

223082_at

−1.8

0.002

NINJ2

ninjurin 2

219594_at

−1.7

0.039

MEST

mesoderm specific transcript homolog (mouse)

202016_at

−1.7

0.010

ITGB1BP2

integrin beta 1 binding protein (melusin) 2

219829_at

−1.6

<0.001

PLXDC1

plexin domain containing 1

219700_at

−1.5

0.006

BPGM

2,3-bisphosphoglycerate mutase

203502_at

−1.5

<0.001

MTFP1

mitochondrial fission process 1

223172_s_at

−1.5

0.004

MAP2K3

mitogen-activated protein kinase kinase 3

215499_at

−1.5

0.003

LRRN4CL

LRRN4 C-terminal like

1556427_s_at

−1.4

0.042

FBXO9

F-box protein 9

210638_s_at212987_at

−1.4

−1.4

<0.001

<0.001

HERC1

HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

218306_s_at

−1.4

<0.001

JARID2

jumonji, AT rich interactive domain 2

203297_s_at

−1.4

<0.001

TRAK1

trafficking protein, kinesin binding 1

202079_s_at

−1.4

0.004

ZNF252P

zinc finger protein 252, pseudogene

228200_at

−1.4

<0.001

PRSS23

protease, serine, 23

202458_at

−1.4

0.030

OLFML2B

olfactomedin-like 2B

213125_at

−1.4

0.049

MSANTD4

Myb/SANT-like DNA-binding domain containing 4 with coiled-coils

227418_at

−1.3

0.043

ZDHHC7

zinc finger, DHHC-type containing 7

218606_at

−1.3

<0.001

RAP2A

RAP2A, member of RAS oncogene family

225585_at

−1.3

0.016

LRP12

low density lipoprotein receptor-related protein 12

219631_at

−1.3

0.050

BMPR1A

bone morphogenetic protein receptor, type IA

213578_at

−1.3

0.001

RNF10

ring finger protein 10

207801_s_at

−1.3

<0.001

COL5A1

collagen, type V, alpha 1

203325_s_at

−1.3

0.007

INSIG1

insulin induced gene 1

201626_at

−1.3

0.046

SLC35E3

solute carrier family 35, member E3

218988_at

−1.3

0.003

MEMO1

dpy-30 homolog (C. elegans) /// mediator of cell motility 1

219065_s_at

−1.3

0.004

MYL4

myosin, light chain 4, alkali; atrial, embryonic

210395_x_at

−1.2

0.002

COX7A2

cytochrome c oxidase subunit VIIa polypeptide 2 (liver)

201597_at

−1.2

0.019

MGAT4B

mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B

224598_at

−1.2

0.003

MRC2

mannose receptor, C type 2

209280_at

−1.2

0.010

  1. FD fold difference. a fold differences for genes with more than one probe set were calculated as the average of the individual values, which did not differ markedly