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Table 3 Correlations between synovial fluid inflammatory cytokines and pain scores, n = 54 (Spearman’s correlation coefficients, p)

From: Correlations between inflammatory cytokines, muscle damage markers and acute postoperative pain following primary total knee arthroplasty

 

PDQ

NRSR

NRSW

T0

T1

T2

T3

T4

T0

T1

T2

T3

T4

PGE2

0.43, 0.001*

0.08, 0.588

0.38, 0.004

0.36, 0.007

0.03, 0.806

0.15, 0.286

0.52, <0.001*

0.33, 0.017

0.29, 0.032

0.26, 0.055

0.14, 0.317

IL-6

0.34, 0.011

0.08, 0.577

0.17, 0.225

0.09, 0.542

−0.22, 0.115

−0.12, 0.409

0.47, <0.001*

0.31, 0.021

0.27, 0.051

0.25, 0.065

0.07, 0.625

IL-8

0.15, 0.264

0.32, 0.019

0.10, 0.464

0.04, 0.763

−0.16, 0.254

−0.21, 0.122

0.74, <0.001*

0.16, 0.235

0.22, 0.109

0.20, 0.157

0.13, 0.350

TNF-α

0.28, 0.043

0.30, 0.029

0.19, 0.159

0.30, 0.028

−0.05, 0.740

−0.15, 0.295

0.76, <0.001*

0.25, 0.069

0.22, 0.116

0.22, 0.111

0.26, 0.062

  1. Abbreviations: NRSR numerical rating scale at rest, NRSW numerical rating scale at walking, PDQ pain disability questionnaire, PGE2 prostaglandin E2, IL interleukin, TNF-α tumor necrosis factor alpha, T0 24 h before surgery, T1-T4 24, 48, 72 h and 5 days after surgery, respectively. The p-values are presented in their raw, uncorrected form, but the statistical significance for multiple comparisons were further corrected using the conservative Bonferroni p value (0.05/15 = 0.003) to control the family-wise error rate, and p < 0.003 are deemed significant (*)
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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