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Table 3 Effect of bisphosphonate use prior to osteoporotic vertebral fracture

From: Effect of teriparatide (rh-PTH 1–34) versus bisphosphonate on the healing of osteoporotic vertebral compression fracture: A retrospective comparative study

 

With prior BP

Without prior BP

p-value

BP group

 Union rate at 6 months

61.0% (11/18)

71.4% (30/42)

0.547

 Union rate at final follow-up

88.9% (16/18)

90.5% (38/42)

1.000

 Time-to-union (months)

8.3 ± 2.1

7.8 ± 1.4

0.827

 

(95% C.I.: 4.2 – 12.5)

(95%C.I.: 5.0 – 10.5)

 

TPD group

 Union rate at 6 months

85.7% (18/21)

94.1% (16/17)

0.613

 Union rate at final follow-up

95.2% (20/21)

100% (17/17)

1.000

 Time-to-union (months)

4.8 ± 0.5

3.4 ± 0.6

0.070

 

(95% C.I.: 3.8 – 5.8)

(95% C.I.: 2.3 – 4.5)

 

p-value

 Union rate at 6 months

0.141

0.084

 

 Union rate at final follow-up

0.586

0.314

 

 Time-to-union

0.115

0.042

 
  1. *p < 0.05, With prior BP: with bisphosphonate use prior to the time of osteoporotic vertebral fracture, Without prior BP: without bisphosphonate use prior to the time of osteoporotic vertebral fracture
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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