Table 2 Comparisons of genotype distributions and allele frequencies of CD40 rs4810485 G > T and rs1883832 C > T between the KOA and control groups
SNP | KOA group | Control group | χ2 | P | OR (95%CI) |
|---|---|---|---|---|---|
rs4810485 G > T | |||||
GG | 44 (33.08%) | 21 (14.69%) | Ref. | ||
GT | 63 (47.37%) | 58 (40.56%) | 4.226 | 0.040 | 0.518 (0.276 ~ 0.974) |
TT | 26 (19.55%) | 64 (44.76%) | 22.95 | < 0.001 | 0.194 (0.097 ~ 0.387) |
GT + TT | 89 (66.92%) | 122 (85.31%) | 12.95 | < 0.001 | 0.348 (0.194 ~ 0.627) |
G allele | 151 (57.14%) | 100 (34.97%) | Ref. | ||
T allele | 115 (42.86%) | 186 (65.03%) | 26.42 | < 0.001 | 0.410 (0.290 ~ 0.577) |
rs1883832 C > T | |||||
CC | 21 (15.79%) | 43 (30.07%) | Ref. | ||
CT | 75 (56.39%) | 74 (51.75%) | 5.553 | 0.019 | 2.075 (1.124 ~ 3.830) |
TT | 37 (27.82%) | 26 (18.18%) | 8.595 | 0.003 | 2.914 (1.413 ~ 6.010) |
CT + TT | 96 (72.18%) | 117 (81.82%) | 0.082 | 1.680 (0.934 ~ 3.024) | |
C allele | 117 (43.98%) | 160 (55.94%) | Refer | ||
T allele | 149 (56.02%) | 126 (44.06%) | 7.884 | 0.005 | 1.617 (1.155 ~ 2.264) |