Assessment of subchondral bone marrow lesions in knee osteoarthritis by MRI: a comparison of fluid sensitive and contrast enhanced sequences

Table 2 Observer agreement for relative and absolute CEA-BML and STIR-BML measurements, and relative N_voxel, irrespective of baseline/follow-up

Method	Area	Image sequence	Observer agreement	CEA-BML, STIR-BML and N_voxel, relative			CEA-BML, STIR-BML and N_voxel, absolute
Method	Area	Image sequence	Observer agreement	Bias^a,%	95% CI		Bias^a, mm³/mm^2b	95% CI
MS	Femur	T1 CE FS	Inter-observer Intra-observer	−0.86 −0.98	−2.68 −2.37	0.95 0.42	−79 −94	−281 −199	122 11
	Tibia	T1 CE FS	Inter-observer Intra-observer	−0.67 −0.89	−4.2 −2.64	2.8 0.86	18 −58	−321 −147	358 31
	Femur	STIR	Inter-observer Intra-observer	−0.36 1.15	−1.45 −0.46	0.73 2.76	7 142	−129 −41	144 325
	Tibia	STIR	Inter-observer Intra-observer	−0.26 1.18	−0.82 −0.06	1.35 2.41	−83 129	−209 6	44 251
CAS	Femur	T1 CE FS	Inter-observer Intra-observer	0.23 −0.37	−1.22 −1.03	1.68 0.29	108 −71	−59 −185	276 43
	Tibia	T1 CE FS	Inter-observer Intra-observer	0.29 0.18	−1.57 −0.30	2.15 0.67	14 3	−94 −36	122 42
	Femur	STIR	Inter-observer Intra-observer	0.01 −0.10	−0.41 −0.42	0.43 0.21	15 67	−60 13	89 121
	Tibia	STIR	Inter-observer Intra-observer	−0.10 0.22	−0.70 −0.04	0.51 0.49	−74 61	−140 28	9 94
Dynamika	Femur Tibia	DCE-MRI	Intra-observer Intra-observer	−2.75 −2.5	−4.56 −5.37	−0.94 0.37	−27 −7	−50 −29	−5 15

ISSN: 1471-2474