| EST (n = 284) | NEW (n = 62) |
---|
baseline | after 1Â year | baseline | after 1Â year |
---|
DAS28 | 2.67 (1.99, 3.70) | 2.58 (1.80, 3.45) | 4.46 (3.77, 5.35) | 2.43 (1.54, 3.57) |
DAS28 Diff | Â | 0.18 (-0.47, 0.87) | Â | 1.92 (0.65, 2.99) |
RADAI-5 | 2.6 (1.2, 4.4) | 2.2 (1.0, 4.0) | 4.4 (3.2, 6.2) | 2.4 (1.2, 3.8) |
RADAI-5 Diff | Â | 0.2 (-0.5, 1.2) | Â | 2.0 (0.6, 3.4) |
HAQ | 0.63 (0.13, 1.19) | 0.63 (0.13, 1.13) | 1.00 (0.63, 1.38) | 0.50 (0.13, 1.25) |
HAQ Diff | Â | 0.00 (-0.13, 0.25) | Â | 0.38 (0.00, 0.63) |
- Abbreviations: DAS28 Disease Activity Score using ESR out of 28 joints, DIFF Difference to baseline after 1 year follow up, ESR Erythrocyte Sedimentation Rate, EST pts with established bDMARD treatment before inclusion in BIOREG of whom a full data set as described is viable, HAQ-DI Health Assessment Questionnaire Disability Index, N number of pts, NEW pts included in BIOREG with start of biologic treatment ± 30 days of whom a full data set as described is viable, PTS patients, RADAI-5 Rheumatoid Arthritis Disease Activity Index-5